Plasmablastic neoplasm in an HIV affected individual and a brief note on its differential diagnosis

Authors

  • Veda Hegde Associate Professor, Department of Oral Pathology, SDM College of Dental Sciences and Hospital, Sattur, Dharwad: 580009, Karnataka
  • Kaveri Hallikeri Professor and HOD, Department of Oral Pathology, SDM College of Dental Sciences and Hospital, Sattur, Dharwad
  • Venkatesh Anehosur Professor and HOD, Department of Oral Surgery, SDM College of Dental Sciences and Hospital, Sattur, Dharwad

DOI:

https://doi.org/10.3126/ajms.v6i3.10762

Keywords:

Acquired immunodefi ciency syndrome, Immunodefi ciency, Lymphoma, Non-Hodgkin’s lymphoma, Diffuse large B cell lymphoma

Abstract

HIV/AIDS predisposes an individual to a variety of malignancies. Lymphomas constitute a group of neoplasm of which are derived from the basic cells of lymphoid tissue, lymphocytes and histiocytes in any of their developmental stages. Thus these neoplasms are closely related and difficult to diagnose based on the histopathology alone. To highlight the importance of immuno-histochemistry in lesions as in the present case and the varied differential diagnosis that is useful to arrive at a diagnosis. We report a case of plasmablastic neoplasm in a young female whose HIV status became apparent only after the histopathologic diagnosis. Oral lesion was the only presenting feature. The lesion was a very aggressive lesion. Diverse differential diagnosis has been illustrated with their specific features which can be valuable to achieve a diagnosis of a particular lymphoma. Although, the histopathology reveals predominantly plasmablasts, it is still not possible to give an accurate diagnosis based on microscopy alone. Thus such lesions have to be differentiated with the help of immuno-histochemistry.

DOI: http://dx.doi.org/10.3126/ajms.v6i3.10762  

Asian Journal of Medical Sciences Vol.6(3) 2015 77-80

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Published

2014-10-09

How to Cite

Hegde, V., Hallikeri, K., & Anehosur, V. (2014). Plasmablastic neoplasm in an HIV affected individual and a brief note on its differential diagnosis. Asian Journal of Medical Sciences, 6(3), 77–80. https://doi.org/10.3126/ajms.v6i3.10762

Issue

Vol. 6 No. 3 (2015)

Section

Case Reports

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