A study of angiographic severity in patients with coronary artery disease and hyperuricemia

Authors

  • Subhraprakash Pramanik RMO Cum Clinical Tutor, General Medicine, Medinipur Medical College, paschim Medinipur, WB
  • Koushik Mondal Senior Resident, Cardiology, Burdwan Medical College, Burdwan, West Bengal
  • Arpan Kumar Dey Consultant Physician, Jalpayguri, West Bengal
  • Pijush Kanti Mandal Assistant Professor, General Medicine, College of Medicine and Sagore Dutta Hospital, Kolkata
  • Shovan Kumar Das Specialist Medical Officer, Ghatal SD Hospital, Purba Midnapore, West Bengal
  • Tanmoy W Momin Consultant Physician, Tura, Meghalaya
  • Mrinmoy Mitra RMO Cum Clinical Tutor, Pulmonary Medicine, Calcutta National Medical College, Kolkata
  • Monojit Mondal Senior Resident, Instiute of Child Health, Kolkata
  • Satyendra Nath Dutta Post-Doctoral Trainee, Cardiology, Medical College, Kolkata

DOI:

https://doi.org/10.3126/ajms.v7i2.12717

Keywords:

Hyperuricemia, Angiographic Severity, Gensini Score, Coronary Artery Disease (CAD).

Abstract

Backgrounds: Hyperuricemia has not yet been established as cardiovascular risk factor. We aimed to study the angiographic severity in patients with coronary artery disease (CAD) and hyperuricemia.

Materials and Methods: In this observational cross-sectional study we measured serum uric acid level in 82 patients of CAD who underwent coronary angiography in catheterisation laboratory of our Institution. Severity of CAD was determined on the basis of Gensini score, number of diseased vessels, critical lesions and total occlusions.

Results: The prevalence of hyperuricemia in patients with CAD was 42.68% in our study. Hyperuricemia was associated with higher Gensini score (33.33±10.64 vs. 22.90±6.75, p value <0.001), number of critical lesions (1.03±0.84 vs. 0.63±0.72, p value 0.031), total occlusions (0.67±0.47 vs. 0.37±0.48, p value 0.007) and dyslipidemia (63.6% vs. 30.6%, p value 0.003) more frequently compared to normouricemic patients. And also the higher serum uric acid level was correlated with higher Gensini score (beta 0.418, t 4.430, p value <0.001, 95% CI 0.036 and 0.094) and frequent number of total occlusion (beta 0.338, t 3.589, p value 0.001, 95% CI 0.462 and 1.613).

Conclusion: Hyperuricemia was associated with higher Gensini score, frequent total occlusions and critical lesions in patients with Coronary Artery Disease compared to patients with normal uric acid level and also it was significantly correlated with higher Gensini score and frequent total occlusions.

Asian Journal of Medical Sciences Vol.7(2) 2015 1-4

Downloads

Download data is not yet available.
Abstract
1002
PDF
1039

Downloads

Published

2015-11-05

How to Cite

Pramanik, S., Mondal, K., Dey, A. K., Mandal, P. K., Das, S. K., Momin, T. W., Mitra, M., Mondal, M., & Dutta, S. N. (2015). A study of angiographic severity in patients with coronary artery disease and hyperuricemia. Asian Journal of Medical Sciences, 7(2), 1–4. https://doi.org/10.3126/ajms.v7i2.12717

Issue

Vol. 7 No. 2 (2016)

Section

Original Articles

License

Authors who publish with this journal agree to the following terms:

  1. The journal holds copyright and publishes the work under a Creative Commons CC-BY-NC license that permits use, distribution and reprduction in any medium, provided the original work is properly cited and is not used for commercial purposes. The journal should be recognised as the original publisher of this work.
  2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
  3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).