A study of risk factors for bacteremia caused by urinary tract infections

Authors

  • Muralidhar Varma Associate Professor, Department of Medicine, Kasturba Medical College, Manipal Academy of Higher Education (MAHE), Manipal, Karnataka, India http://orcid.org/0000-0002-5546-5353
  • Sravan Kumar Peravali Post Graduate Student, Department of Medicine, Kasturba Medical College, Manipal Academy of Higher Education (MAHE), Manipal, Karnataka, India http://orcid.org/0000-0003-0069-1270
  • Vandana KE Professor, Department of Microbiology, Kasturba Medical College Manipal Academy of Higher Education (MAHE), Manipal, Karnataka, India http://orcid.org/0000-0001-7561-4435
  • Asha Kamath Professor and Head, Department of Statistics, Prasanna School of Public Health, Manipal Academy of Higher Education (MAHE), Manipal, Karnataka, India http://orcid.org/0000-0003-0727-8067
  • Rahul Singh Intern, Department of Medicine, Kasturba Medical College, Manipal Academy of Higher Education (MAHE), Manipal, Karnataka, India http://orcid.org/0000-0001-9271-2037

DOI:

https://doi.org/10.3126/ajms.v9i5.19907

Keywords:

Risk factors, Bacteremia, UTI

Abstract

Background: Urinary tract infections are not only one of the most common infections, but also one of the most common sources of bacteremia in both the general population and hospitalized patients.

Aims and Objectives: The objective of this study was to identify risk factors for bacteremia caused by urinary tract infections.

Materials and Methods: This was a prospective case control study conducted from October 2012 to July 2014in a tertiary care teaching hospital in southern India. Urinary tract infections were diagnosed based on the CDC criteria.Patients witha set of blood cultures and urine culture isolating same organism were grouped as cases while patients with urine culture alone isolating organism with sterile blood cultures were identified as controls.

Results: Out of the 198 patientsin the study, 66 were cases while 132 were controls. E coli was the most organism isolated (81% of cases and 66% of controls). Risk factors for bacteremia based on univariate and multivariate analysis were diabetes mellitus with uncontrolled sugars (univariate: p=0.001; OR=5.250 [2.044-13.582]; and multivariate: p=0.01; OR= 6.023 [1.52-23.51]) and pyelonephritis (univariate: p=0.001; OR=6.56 [2.87-1.48]; and multivariate: p=0.047; OR=4.95 [1.02-24.12]).

Conclusion: Upper UTI and complicated UTI patients should be evaluated for bacteremia since prompt and targeted treatment may be required.

Asian Journal of Medical Sciences Vol.9(5) 2018 25-30

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Author Biographies

Muralidhar Varma, Associate Professor, Department of Medicine, Kasturba Medical College, Manipal Academy of Higher Education (MAHE), Manipal, Karnataka, India

Associate Professor, Department of Medicine

Sravan Kumar Peravali, Post Graduate Student, Department of Medicine, Kasturba Medical College, Manipal Academy of Higher Education (MAHE), Manipal, Karnataka, India

Post Graduate, Department of Medicine

Vandana KE, Professor, Department of Microbiology, Kasturba Medical College Manipal Academy of Higher Education (MAHE), Manipal, Karnataka, India

Professor, Department of Microbiology

Asha Kamath, Professor and Head, Department of Statistics, Prasanna School of Public Health, Manipal Academy of Higher Education (MAHE), Manipal, Karnataka, India

Professor and Head, Department of Statistics

Rahul Singh, Intern, Department of Medicine, Kasturba Medical College, Manipal Academy of Higher Education (MAHE), Manipal, Karnataka, India

MBBS Graduate, Department of Medicine

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Published

2018-08-31

How to Cite

Varma, M., Peravali, S. K., KE, V., Kamath, A., & Singh, R. (2018). A study of risk factors for bacteremia caused by urinary tract infections. Asian Journal of Medical Sciences, 9(5), 25–30. https://doi.org/10.3126/ajms.v9i5.19907

Issue

Vol. 9 No. 5 (2018)

Section

Original Articles

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