To Correlate Serum Ferritin Levels with Clinical Outcome in Covid-19 Patients

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DOI:

https://doi.org/10.3126/ajms.v12i5.34371

Keywords:

COVID-19, Serum ferritin, cytokine storm

Abstract

Background: COVID-19 a pandemic, affecting worldwide causing significant morbidity and to some extent mortality needs to be evaluated and urgently identify reliable predictors of disease severity and outcome. The fatal outcomes by COVID-19 are accompanied by cytokine storm syndrome. The cytokine storm is determined by serum ferritin.

Aims and Objective: To determine the role of Serum ferritin in assessing the severity and outcome of COVID-19.

Materials and Methods: A single-center, cross-sectional, observational study was conducted among SARS-CoV-2 infected patients from March 2020 to May 2020. The diagnosis was confirmed by real-time polymerase chain reaction (RT-PCR). Serum ferritin levels were compared with the treatment outcomes of COVID-19 positive patients.

Results: A total of 1977 COVID-19 patients were studied. The mean age was 43.89±15.58 years and had male preponderance of 61.56% of the total subjects. The mean serum ferritin levels among recovered and expired patients were 1225.6 ± 2502.91 ng/ml and 285.71 ± 391.99 ng/ml, respectively.

Conclusion: Serum ferritin was markedly increased in COVID-19 patients who could not survive as compared to the patients who finally recovered from the infection, proving it as a useful marker for assessing the severity of COVID-19.

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Published

2021-05-01

How to Cite

Rajanna, A. H., Krishnegowda, R., & Govindaiah, R. M. (2021). To Correlate Serum Ferritin Levels with Clinical Outcome in Covid-19 Patients. Asian Journal of Medical Sciences, 12(5), 25–29. https://doi.org/10.3126/ajms.v12i5.34371

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Section

Original Articles