The short term visual, refractive and Topographic outcome of Corneal Collagen Crosslinking in Keratoconus

Authors

  • Renuga Devi Kaliaperumal Assistant Professor, Department of Ophthalmology, Sri Manakula Vinayagar Medical College https://orcid.org/0000-0002-7948-7557
  • Amudha Purushothaman Assistant Professor, Department of Ophthalmology, Indira Gandhi Medical College https://orcid.org/0000-0002-6211-8579
  • Thiruvengada Krishnan Professor and Head, Cornea Clinic, Aravind Eye Hospital, Puducherry, India
  • Shivananda Consultant, Cornea Clinic, Aravind Eye Hospital, Puducherry, India

DOI:

https://doi.org/10.3126/ajms.v12i11.38768

Keywords:

Keratoconus, Collagen cross linking, Riboflavin, UVA irradiation

Abstract

Background: Keratoconus is a condition characterized by biomechanical instability of cornea presenting in a progressive asymmetry and bilateral way. Corneal collagen cross-linking with riboflavin and UVA is a technique that has influenced the treatment of Keratoconus by arresting the progression.

Aims and Objectives: The aim of the study was to assess the short-term efficacy and safety of collagen cross-linking in Keratoconus.

Materials and Methods: This prospective, nonrandomized, interventional case study was conducted at Aravind Eye hospital and PGI, Puducherry from June 2012 to April 2013. Statistical analysis was done using repeated measures ANOVA and Bonferonn’s using IBM SPSS Inc. 20.Version.

Results: A total of 30 patients were enrolled in this study and standard cross linking procedure was done. It was found that UCVA, BSCVA both improved about 40%. Spherical Equivalent reduced by 0.7 D, cylinder reduced by 0.8 D and total astigmatism decreased by about 0.4 D. Steepest K value reduced by 2 D, Irregularity and astigmatism at 3 and 5 mm also changed significantly (P<0.05).

Conclusion: Collagen cross-linking arrests the progression of Keratoconus. It seems to improve the UCVA and BCVA and it is a safe and effective procedure.

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Published

2021-11-01

How to Cite

Kaliaperumal, R. D. ., Purushothaman, A. ., Krishnan, T. ., & Shivananda. (2021). The short term visual, refractive and Topographic outcome of Corneal Collagen Crosslinking in Keratoconus. Asian Journal of Medical Sciences, 12(11), 66–70. https://doi.org/10.3126/ajms.v12i11.38768

Issue

Vol. 12 No. 11 (2021)

Section

Original Articles

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Copyright (c) 2021 Asian Journal of Medical Sciences

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