Effect of B complex vitamins on life quality and neuropathic pain intensity in patients undergoing hemodialysis

Authors

  • José Eduardo Nogueira Forni Assistant Professor, Department of Orthopedics and Traumatology, Faculdade de Medicina de São José do Rio Preto, São José do Rio Preto, São Paulo, Brazil https://orcid.org/0000-0003-1269-003X
  • Ana Carolina Rodrigues Medical Student, Department of Orthopedics and Traumatology, Faculdade de Medicina de São José do Rio Preto, São José do Rio Preto, São Paulo, Brazil https://orcid.org/0000-0002-0883-5948
  • Amanda Fidalgo Lima Medical Student, Department of Orthopedics and Traumatology, Faculdade de Medicina de São José do Rio Preto, São José do Rio Preto, São Paulo, Brazil https://orcid.org/0000-0003-0449-9649
  • Bianca de Oliveira Lemos Medical Student, Department of Orthopedics and Traumatology, Faculdade de Medicina de São José do Rio Preto, São José do Rio Preto, São Paulo, Brazil https://orcid.org/0000-0002-8665-734X
  • Beatriz Arid Rudnick Medical Student, Department of Orthopedics and Traumatology, Faculdade de Medicina de São José do Rio Preto, São José do Rio Preto, São Paulo, Brazil https://orcid.org/0000-0001-9690-7739
  • Gabriela Modulo Molina Medical Student, Department of Orthopedics and Traumatology, Faculdade de Medicina de São José do Rio Preto, São José do Rio Preto, São Paulo, Brazil https://orcid.org/0000-0003-2116-6133
  • Narayana Silva Paiva Medical Student, Department of Orthopedics and Traumatology, Faculdade de Medicina de São José do Rio Preto, São José do Rio Preto, São Paulo, Brazil https://orcid.org/0000-0001-9747-0188

DOI:

https://doi.org/10.3126/ajms.v13i3.39472

Keywords:

Chronic pain, Chronic renal failure, Drug therapy, Pain, Quality of life

Abstract

Background: Neuropathic pain (NP) is characterized by chronic pain with a generally strong intensity that leads to limitations regarding activities of daily living.

Aims and Objectives: The aim of the study was to investigate the effect of B complex vitamins on NP intensity and life quality in patients undergoing hemodialysis.

Materials and Methods: A randomized controlled double-blind clinical trial was conducted among hemodialysis patients with clinical diagnosis of NP randomly allocated to two groups: A (gabapentin) and B (B vitamins). DN4, visual analog scale, and Kidney Disease Quality of Life-Short Form questionnaire were used to identify NP, measure pain intensity, and assess quality of life, respectively.

Results: A significant reduction in pain occurred after treatment with gabapentin (P=0.003). In the B group, the reduction of pain went from a mean of 7.27 to 5.09 after treatment (P=0.056). In the A group, a significantly poorer quality of life was reported after treatment in the social relations domain (P=0.010). A significant improvement in quality of life and environment domains (P=0.025 and 0.049, respectively) was reported after use of B vitamins.

Conclusion: These findings demonstrate that B complex vitamins for the treatment of NP in hemodialysis patients should be investigated further, as this form of treatment contributed to a reduction in pain intensity and suffering with no side effects and at low cost.

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Published

2022-03-01

How to Cite

Forni, J. E. N. ., Ana Carolina Rodrigues, Amanda Fidalgo Lima, Bianca de Oliveira Lemos, Beatriz Arid Rudnick, Gabriela Modulo Molina, & Narayana Silva Paiva. (2022). Effect of B complex vitamins on life quality and neuropathic pain intensity in patients undergoing hemodialysis. Asian Journal of Medical Sciences, 13(3), 43–47. https://doi.org/10.3126/ajms.v13i3.39472

Issue

Vol. 13 No. 3 (2022)

Section

Original Articles

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Copyright (c) 2022 Asian Journal of Medical Sciences

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