Phytochemical and antimicrobial properties of the methanolic extracts of <i>Bombax buonopozense</i> leaf and root

Authors

  • Godwin C Akuodor Dept. of Pharmacology and Toxicology, National Institute for Pharmaceutical Research and Development, Garki, Abuja
  • Augustine D Essien Dept. of Pharmacology and Toxicology, National Institute for Pharmaceutical Research and Development, Garki, Abuja
  • Jemilat A Ibrahim Department of Medicinal Plant Research and Traditional Medicine, National Institute for Pharmaceutical Research and Development (NIPRD), Abuja
  • Augustine Bassey Department of Pharmacology, Faculty of Clinical Medicine, University of Uyo
  • Joseph L Akpan Department of Pharmacology, Faculty of Clinical Medicine, Ebonyi State University, Abakaliki
  • Nwakaego C Ikoro Department of Optometry and Optical Technology, Federal University of Technology, Owerri
  • Simon C Onyewenjo Department of Biology and Microbiology, Federal Polytechnic Nekede

DOI:

https://doi.org/10.3126/ajms.v2i3.4222

Keywords:

Bombax buonopozense, phytochemical, antimicrobial agent, medicinal plant

Abstract

Objective: The leaf and root of Bombax buonopozense which have some ethnomedicinal applications were subjected to phytochemical screening and antimicrobial activity against some disease causing microorganisms.

Material & Methods: The phytochemical composition was evaluated using standard procedures. Susceptibility of these clinical isolates (Staphylococcus aureus, Bacillus subtilis, Klebsiella pneumonae, Proteus spp. and Escherichia coli) to the extracts was determined using the agar diffusion method.

Results: Phytochemical screening revealed the presence of alkaloids, flavonoids, tannins, saponins, terpenoids, steroids, phlobatannins, anthraquinones and carbohydrates (mostly in root). The root extract demonstrated antibacterial activity against all the organisms tested, while the leaf extract had activity on S. aureus and B. subtilis only.

Conclusion: The findings indicate that the root extract contain the most active components which may be used to source antibiotic substances for possible treatment of bacterial infections.

DOI: http://dx.doi.org/10.3126/ajms.v2i3.4222

Asian Journal of Medical Sciences 2 (2011) 190-194

 

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Published

2012-04-24

How to Cite

Akuodor, G. C., Essien, A. D., Ibrahim, J. A., Bassey, A., Akpan, J. L., Ikoro, N. C., & Onyewenjo, S. C. (2012). Phytochemical and antimicrobial properties of the methanolic extracts of <i>Bombax buonopozense</i> leaf and root. Asian Journal of Medical Sciences, 2(3), 190–194. https://doi.org/10.3126/ajms.v2i3.4222

Issue

Vol. 2 No. 3 (2011)

Section

Original Articles

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