To study the effect of oral supplementation Vitamin D during pregnancy and status of cord blood

Authors

DOI:

https://doi.org/10.3126/ajms.v13i9.45296

Keywords:

Vitamin D; Cord blood; Oral supplementation

Abstract

Background: In many nations, low Vitamin D levels in pregnant women have been associated to adverse outcomes for the mother, her baby, and the birth itself.

Aims and Objectives: To study the effect of oral supplementation of mothers with high dose vitamin D (2000IU/day) in comparison with maintenance dose (400IU/day) during pregnancy on vitamin D status of cord blood at the time of delivery.

Materials and Methods: Randomized single blind controlled trial conducted in 112 mothers recruited in first trimester, randomized into two groups. One group of mothers received 2000 IU/day, one group 400 IU/day till delivery. Mothers are followed up till delivery age, weight, height, and dressing.

Results: Vitamin D levels in mothers in study group were showing 88% insufficiency (<20 ng/ml) and 12% sufficiency (>20 ng/ml). Mean values in both groups that is Group A 6.6±2.8, in Group B 6.2±2.2, both means are comparable with P=0.47, but after supplementation mean maternal Vitamin D level that is 13.4±3.6, with P≤0.0001, this shows that there is a statistically significant. There is a statistically significant correlation is observed between maternal and cord blood Vitamin D levels after supplementation. Statistically significant correlation was observed between maternal and cord blood Vitamin D levels.

Conclusions: Vitamin D supplementation throughout pregnancy enhances maternal serum and Vitamin D levels at term, according to this study. There is currently sufficient high-quality evidence pertaining to the therapeutic effects of Vitamin D supplementation during pregnancy.

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Published

2022-09-01

How to Cite

Sravanthi Veldanadi, Kavitha Vislavath, Archana Challa, Praveen Dussa, & Vasudeva Murali. (2022). To study the effect of oral supplementation Vitamin D during pregnancy and status of cord blood. Asian Journal of Medical Sciences, 13(9), 117–124. https://doi.org/10.3126/ajms.v13i9.45296

Issue

Vol. 13 No. 9 (2022)

Section

Original Articles

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Copyright (c) 2022 Asian Journal of Medical Sciences

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