Managing childhood acute lymphoblastic leukemia in a child with Emery-Dreifuss muscular dystrophy

Authors

  • Aishvarya Diptivilasa Junior Resident, Department of Pediatric Hematology Oncology, Post Graduate Institute of Child Health, Noida, Uttar Pradesh, India
  • Nita Radhakrishnan Associate Professor, Department of Pediatric Hematology Oncology, Post Graduate Institute of Child Health, Noida, Uttar Pradesh, India https://orcid.org/0000-0002-7941-5641
  • Shruti Verma IAP Fellow, Department of Pediatric Hematology Oncology, Post Graduate Institute of Child Health, Noida, Uttar Pradesh, India

DOI:

https://doi.org/10.3126/ajms.v15i1.56842

Keywords:

Cancer; Muscular dystrophy; Cancer genetics

Abstract

Genetics is increasingly being integrated into clinical oncology practice. It is necessary for risk stratification of disease, for prognostication, for recognition of underlying predisposition, and for recognition of potential toxicity and predicting outcomes. The prevalence of genetic syndromes, their clinical significance, effect on cancer, and its treatment have been defined in recent times. In this present work, we describe the challenges we faced while managing a child with acute lymphoblastic leukemia with an underlying rare muscular dystrophy. The details were recorded from case files and prospectively collected data. Dose modification of certain chemotherapeutic drugs was planned to reduce toxicity in the child. The child responded to treatment and is currently in remission. The recognition of genetic entity and their potential interactions with treatment received for cancer is vital to plan the treatment.

Downloads

Download data is not yet available.
Abstract
53
PDF
69

Downloads

Published

2024-01-01

How to Cite

Diptivilasa, A., Radhakrishnan, N., & Verma, S. (2024). Managing childhood acute lymphoblastic leukemia in a child with Emery-Dreifuss muscular dystrophy. Asian Journal of Medical Sciences, 15(1), 272–274. https://doi.org/10.3126/ajms.v15i1.56842

Issue

Vol. 15 No. 1 (2024)

Section

Case Reports

License

Copyright (c) 2023 Asian Journal of Medical Sciences

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Authors who publish with this journal agree to the following terms:

  1. The journal holds copyright and publishes the work under a Creative Commons CC-BY-NC license that permits use, distribution and reprduction in any medium, provided the original work is properly cited and is not used for commercial purposes. The journal should be recognised as the original publisher of this work.
  2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
  3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).