TY - JOUR AU - Attia, Kamal A. AU - El-Badawi, Ashraf A. PY - 2015/06/25 Y2 - 2024/03/28 TI - Effects of Short or Long-Term Exposure of Dithiopyr on Certaine Blood, Growth and Tissue Biochemical Parameters in Catfish (Clarias garipinus) JF - International Journal of Applied Sciences and Biotechnology JA - Int J Appl Sci Biotechnol VL - 3 IS - 2 SE - Research Articles: Biological Sciences DO - 10.3126/ijasbt.v3i2.12686 UR - https://www.nepjol.info/index.php/IJASBT/article/view/12686 SP - 314-321 AB - <p>In the current study the effects of acute or chronic exposure of dithiopyr herbicide (weed controllers) in Catfish (<em>Clarias garipinus</em>) was studied. LC50 was determined, and recorded as 460 &mu;gl<sup>-1</sup>. Acute and chronic effects on certain blood, growth and tissue biochemical parameters were studied as a function of exposure time. Exposure of <em>Clarias garipinus </em>to acute or chronic toxicity of the herbicide resulted in significant increase in glucose, total cholesterol, creatinine, uric acid and Lactate dehydrogenase (LDH) in the herbicide-treated group, while aspartate aminotransferase (AST) and alanine aminotransferase (ALT) showed a fluctuating activities in both exposures. In contrast, there was significantly (P&lt;0.01) lower values for liver and muscle glycogen in acute toxicity as compared with the control group. Also, in herbicide exposed fish a significant reduction in growth parameters was recorded. These alterations could be attributed to the changes in the metabolic pathways of the studied fish that meight be takes place as a secondary response in the fish to provide energy for the "fight-or-flight" reaction and to compensate the high energy demand. This study implies the importance of previous knowledge about the susceptibility of cultured fish species before using herbicides.</p><p>Int J Appl Sci Biotechnol, Vol 3(2): 314-321</p> <p>DOI: <a href="http://dx.doi.org/10.3126/ijasbt.v3i2.12686">http://dx.doi.org/10.3126/ijasbt.v3i2.12686</a></p><p>&nbsp;</p> ER -