TY - JOUR AU - Kumari, Manisha AU - Verma, Rohit Kumar AU - Roy, Prabhat Kumar PY - 2018/06/29 Y2 - 2024/03/29 TI - Effect of Carbafuran Pesticide on Mitotic Chromosomes of Mus musculus JF - International Journal of Applied Sciences and Biotechnology JA - Int J Appl Sci Biotechnol VL - 6 IS - 2 SE - Research Articles: Biological Sciences DO - 10.3126/ijasbt.v6i2.20434 UR - https://www.nepjol.info/index.php/IJASBT/article/view/20434 SP - 169-173 AB - <p>The Genotoxic effect of the carbafuran pesticide was evaluated in the metaphasic chromosomes of bone marrow cells of female Swiss albino mice, <em>Mus musculus<strong> </strong></em>. Six week old mice were put into different groups(six mice per group) and treatment were done according to experimental plan (CLD<sub>15 </sub>i.e. lower dose =30ppm or 0.03mg/ml and CHD<sub>30 </sub>i.e. higher dose =300ppm or 0.3mg/ml).The test material was administered orally for 15 days in CLD<sub>15</sub> and for 30 days in CHD<sub>30</sub> test groups of female mice. The result revealed that the frequency of chromosomal abnormalities i.e. structural and numerical changes were11.5% in control, 74.0%in CLD<sub>15 </sub>and 99.0%in CHD<sub>30</sub>, respectively in bone marrow cells of female mice.</p><p><em>Int. J. Appl. Sci. Biotechnol. Vol 6(2): 169-173</em></p><p> </p> ER -