Patient with false negative RT-PCR for COVID-19 referred to cancer hospital for lung cancer screening: A case report

Authors

DOI:

https://doi.org/10.3126/jbs.v8i2.41961

Keywords:

COVID-19, HRCT, lung cancer, Nepal, pneumonia, RT-PCR

Abstract

Background: Even though RT-PCR tests are generally considered the gold standard for diagnosing SARS-CoV-2, they are not without flaws, and the likelihood of detecting an infection varies depending on when the test is performed. There is chance of false negative due to different pitfalls. So there is essential of correlation of radiological characteristics, abnormalities in biochemical tests and symptoms of suspected patient during COVID-19 epidemic.

Case presentation: Herein, we report a 42-year-old male patient with high-grade fever, dry cough, headache and dizziness. He went for the RT-PCR test two times and reported negative. On the chest X-Ray, there was opacity on both lungs and referred to cancer-hospital for lung-cancer screening. The patient underwent chest-HRCT and laboratory tests for further evaluation and was identified as typical COVID-19 findings. Then the patient was isolated and treatment of given according to COVID-19 treatment guidelines  

Conclusion: It is concluded that a clinically symptomatic patient with typical chest HRCT and abnormal lab findings for COVID-19 should be considered as a COVID-19 patient and isolated even with two negative RT-PCR tests.

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Author Biographies

Ajay Kumar Yadav, The Second Affiliated Hospital of Chongqing Medical University, PR China

Department of Nuclear Medicine

Suman Gnawali, BP Koirala Memorial Cancer Hospital, Bharatpur, Nepal

Technologist BMIT, Department of Radiology & Nuclear Medicine

Sandip Mandal, BP Koirala Memorial Cancer Hospital, Bharatpur, Nepal

Technologist BMIT, Department of Radiology & Nuclear Medicine

Gyan Bahadur Shrestha, BP Koirala Memorial Cancer Hospital, Bharatpur, Nepal

Senior Consultant, Department of Radiology & Nuclear Medicine

Gangbiao Yuan, The Second Affiliated Hospital of Chongqing Medical University, PR China

Professor, Department of Nuclear Medicine

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Published

2021-12-31

How to Cite

Yadav, A. K., Gnawali, S., Mandal, S., Shrestha, G. B., & Yuan, G. (2021). Patient with false negative RT-PCR for COVID-19 referred to cancer hospital for lung cancer screening: A case report. Journal of Biomedical Sciences, 8(2), 50–54. https://doi.org/10.3126/jbs.v8i2.41961

Issue

Section

Case Reports & Case Series