Journal of Biomedical Sciences https://www.nepjol.info/index.php/JBS <p>Official journal of the Nepal Health Research Society.</p> <p>JBS is currently accepting submissions by Email – <a href="mailto:jbs.editors@gmail.com">jbs.editors@gmail.com</a></p> <p><strong>Publication fee 3000 NPR for Nepalese citizens, others all countries $30.</strong></p> Nepal Health Research and Welfare Society en-US Journal of Biomedical Sciences 2676-1343 Paediatric Asthma associated with passive smoking and garbage burning: A case report from Kedah, Malaysia https://www.nepjol.info/index.php/JBS/article/view/26160 <p><strong>Background </strong>Combatting with childhood asthma is a global challenge. Exposure to allergens, air pollutants, tobacco smoke, cold air, viral infection, and family history, are the few major causative factors for asthma. An eleven years old boy from Kedah, Malaysia, had the first asthmatic attack at the age of eight. Possible causes behind the development of his asthmatic attack include passive smoking, environment pollutant created by open residential burning of rubbish practiced by his family members, repeated exposure to allergens such as pollen, house dust mite, animal dander, and eczema. The patient has been treated with inhaled salbutamol BP (100μg/day), oral montelukast Na (5 mg/day) and mometasone furoate (55mcg. once daily). In conclusion, episodes of asthmatic attacks were mainly correlated with passive smoking &amp; burning garbages. Comprehensive approaches such as health education, avoidance of the allergen, cleaning, and maintaining these practices can prevent the development of this morbid illness. &nbsp;</p> Tahmina Afrose Soo Chun Yeou Loh Zhen Xi Kevin Fernandez Narin Habib Suprava Das ##submission.copyrightStatement## http://creativecommons.org/licenses/by/4.0 2019-10-27 2019-10-27 6 1 1 5 10.3126/jbs.v6i1.26160 The status of development of nanoparticle-based swine influenza vaccines: A review https://www.nepjol.info/index.php/JBS/article/view/26161 <p class="Default"><strong><span style="font-size: 10.0pt;">Background </span></strong><span style="font-size: 10.0pt;">Swine are the most important meat animal, famous for white meat, which are prepared as ham, bacon, gammon, sausages and pork. Swine are valuable animals and they are physiologically, immunologically and anatomically similar to humans and their organ can be transplanted to the humans. Due to modernization, the cultural food restriction has lost in the people of urban communities and among the younger generations in Nepal. Gradually changing feeding habit of Nepalese has proven pork to be a useful addition to the food menu. Not only 8.7 lakhs swine in Nepal but the global pig population which occupy 769.05 million are suffering every day from new challenges and threats from very harmful pathogens and diseases like swine dysentery, coccidiosis, swine influenza, etc. Swine influenza is highly contagious rapidly spreading zoonotic viral disease of pigs characterized by febrile respiratory disease often complicated with secondary bacterial infections. Vaccines are only tool for prophylactic measures. There is big challenge for vaccine researchers, manufacturers and scientists for development of effective vaccine regarding swine influenza. Currently available flu vaccines are capable of homologous protection of virus but fail to induce cross protection against frequently evolving heterologous viruses. In this review, we discuss the status of novel nanoparticle-based approach of swine influenza virus vaccine development contributed significantly by Nepalese scientist and the future directions to control this economically important swine disease.</span></p> Uddab Poudel Saurav Pantha Krishna Kaphle ##submission.copyrightStatement## http://creativecommons.org/licenses/by/4.0 2019-10-27 2019-10-27 6 1 6 11 10.3126/jbs.v6i1.26161