Phenytoin induced severe agranulocytosis and hepatitis

Authors

  • N S Neki Govt. Medical College, Guru Nanak Dev Hospital, Amritsar
  • D M Shah Govt. Medical College, Guru Nanak Dev Hospital, Amritsar

Keywords:

Agranulocytosis, Hepatitis, Phenytoin

Abstract

Phenytoin is an anti epileptic drug. It is the cornerstone in the treatment of epilepsy disorders. It causes many adverse drug reactions. Neurological complications are commonly observed. Rarely it may cause idiosyncratic reactions in the form of agranulocytosis, hepatitis. Though rare it may pose a serious problem. The treatment is withdrawal of phenytoin and use of appropriate antibiotic. 
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Author Biographies

N S Neki, Govt. Medical College, Guru Nanak Dev Hospital, Amritsar

Medicine

D M Shah, Govt. Medical College, Guru Nanak Dev Hospital, Amritsar

Medicine

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Published

2017-02-20

How to Cite

Neki, N. S., & Shah, D. M. (2017). Phenytoin induced severe agranulocytosis and hepatitis. Journal of Chitwan Medical College, 6(3), 67-68. https://doi.org/10.3126/jcmc.v6i3.16703

Issue

Vol. 6 No. 3 (2016)

Section

Case Reports

How to Cite

Neki, N. S., & Shah, D. M. (2017). Phenytoin induced severe agranulocytosis and hepatitis. Journal of Chitwan Medical College, 6(3), 67-68. https://doi.org/10.3126/jcmc.v6i3.16703