TY - JOUR AU - Lamichhane, Apar AU - Nakarmi, Kiran Kishor AU - Dahal, Peeyush AU - Basnet, Surendra Jung AU - Pokharel, Pashupati Babu AU - Bhattarai, Suraj AU - Rai, Shankar Man PY - 2019/10/01 Y2 - 2024/03/28 TI - Bacteriological Profile of Burn Patients and Antimicrobial Susceptibility Pattern of their Wound Isolates at Nepal Cleft and Burn Center JF - Journal of College of Medical Sciences-Nepal JA - J Coll Med Sci-Nepal VL - 15 IS - 3 SE - Original Articles DO - 10.3126/jcmsn.v15i3.24363 UR - https://www.nepjol.info/index.php/JCMSN/article/view/24363 SP - 160-166 AB - <p><strong>Background: </strong>Burn infections are the major causes of morbidity and mortality in burn patients. The infectious agent could be both Gram positive and Gram negative bacteria. The aim of this research was to study the bacteriological profile of burn patients and anti-microbial susceptibility pattern of their wound isolates.</p><p>&nbsp;<strong>Methods: </strong>This cross-sectional study was conducted in Kirtipur Hospital, Nepal from January 1<sup>st</sup> to March 31<sup>st</sup> 2019. A total of 109 burn patients were included and their wound swabs were collected at the time of admission. All isolates were identified by standardized microbiological procedures. Anti-microbial susceptibility tests were performed by Kirby Bauer disc diffusion method.</p><p><strong>Results: </strong>Of 109 burn wound samples, 56 (59%) yielded culture growth and the Gram negative isolates were more common than Gram positives (77% vs. 23%). The most common organism isolated was Klebsiella spp. (25%) followed by Acinetobacter spp. (21%) and Staphylococcus aureus (18%). Most burn wound isolates were of resistant strain. Particularly, highly resistant strain of Acinetobacter spp. were isolated, most of which were sensitive to Tigecycline, Polymyxin B and Colistin only.</p><p><strong>Conclusion : </strong>Gram negative isolates were common in burn wound isolates and the antibiotic susceptibility pattern was different for different organisms. The use of antimicrobials should be judicious to further not escalate the problem of antimicrobial resistance in the healthcare settings.</p><p>&nbsp;</p> ER -