Pharmacological effects of traditional herbal plant garlic (Allium sativum): A review

  • Keshab Raj Paudel Department of Pharmacology Kathmandu Medical College and Teaching Hospital, Kathmandu
Keywords: Allicin, Alliin, Allium sativum, Garlic

Abstract

This study aimed to review the different pharmacological effects of garlic. Garlic, Allium sativum, is a herbal plant which has been used in different food preparations since long time. Many studies have shown that allicin is the main compound in garlic which is generated from alliin with the help of alliinase enzyme and is responsible for many pharmacological effects. Different studies have shown that garlic has pharmacological effects such as antihypertensive, antihypercholesterolaemic, antiplatelet, hypoglycaemic, cardioprotective, antimicrobial, antineoplastic, etc. However, studies in the literature have
some confl icting fi ndings and meta-analyses are also slightly different for different effects. Despite these fi ndings, most of the studies, including meta-analyses, have shown signifi cant antihypertensive and hypolipidaemic effects of garlic. Based on the data in the literature, regular dietary consumption of raw garlic, two to four grams, equivalent to one clove of garlic, or 600-900 mg garlic powder per day, if not contraindicated, may be effective for different benefi cial
pharmacological effects.

Journal of Kathmandu Medical College
Vol. 3, No. 4, Oct.-Dec., 2014
Page: 158-161

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Author Biography

Keshab Raj Paudel, Department of Pharmacology Kathmandu Medical College and Teaching Hospital, Kathmandu
Assistant Professor
Published
2015-09-16
How to Cite
Paudel, K. (2015). Pharmacological effects of traditional herbal plant garlic (Allium sativum): A review. Journal of Kathmandu Medical College, 3(4), 158-161. https://doi.org/10.3126/jkmc.v3i4.13375
Section
Review Articles