Pharmacological effects of traditional herbal plant garlic (Allium sativum): A review

Authors

  • Keshab Raj Paudel Department of Pharmacology Kathmandu Medical College and Teaching Hospital, Kathmandu

DOI:

https://doi.org/10.3126/jkmc.v3i4.13375

Keywords:

Allicin, Alliin, Allium sativum, Garlic

Abstract

This study aimed to review the different pharmacological effects of garlic. Garlic, Allium sativum, is a herbal plant which has been used in different food preparations since long time. Many studies have shown that allicin is the main compound in garlic which is generated from alliin with the help of alliinase enzyme and is responsible for many pharmacological effects. Different studies have shown that garlic has pharmacological effects such as antihypertensive, antihypercholesterolaemic, antiplatelet, hypoglycaemic, cardioprotective, antimicrobial, antineoplastic, etc. However, studies in the literature have
some confl icting fi ndings and meta-analyses are also slightly different for different effects. Despite these fi ndings, most of the studies, including meta-analyses, have shown signifi cant antihypertensive and hypolipidaemic effects of garlic. Based on the data in the literature, regular dietary consumption of raw garlic, two to four grams, equivalent to one clove of garlic, or 600-900 mg garlic powder per day, if not contraindicated, may be effective for different benefi cial
pharmacological effects.

Journal of Kathmandu Medical College
Vol. 3, No. 4, Oct.-Dec., 2014
Page: 158-161

Downloads

Download data is not yet available.
Abstract
3468
PDF
1184

Author Biography

Keshab Raj Paudel, Department of Pharmacology Kathmandu Medical College and Teaching Hospital, Kathmandu

Assistant Professor

Downloads

Published

2015-09-16

How to Cite

Paudel, K. R. (2015). Pharmacological effects of traditional herbal plant garlic (Allium sativum): A review. Journal of Kathmandu Medical College, 3(4), 158–161. https://doi.org/10.3126/jkmc.v3i4.13375

Issue

Vol. 3 No. 4 (2014)

Section

Review Articles

License

Copyright © Journal of Kathmandu Medical College
The ideas and opinions expressed by authors or articles summarized, quoted, or published in full text in this journal represent only the opinions of the authors and do not necessarily reflect the official policy of Journal of Kathmandu Medical College or the institute with which the author(s) is/are affiliated, unless so specified.

Authors convey all copyright ownership, including any and all rights incidental thereto, exclusively to JKMC, in the event that such work is published by JKMC. JKMC shall own the work, including 1) copyright; 2) the right to grant permission to republish the article in whole or in part, with or without fee; 3) the right to produce preprints or reprints and translate into languages other than English for sale or free distribution; and 4) the right to republish the work in a collection of articles in any other mechanical or electronic format.