Antibiotic susceptibility pattern of bacterial isolates from quantitative culture of bronchoalveolar lavage fluid in patients with clinical suspicion of pneumonia

Authors

  • Beena Jha Assistant Professor, Department of Microbiology, Kathmandu Medical College Teaching Hospital, Kathmandu, Nepal https://orcid.org/0000-0002-8079-6365
  • Manisha Sharma Assistant Professor, Department of Microbiology, Kathmandu Medical College Teaching Hospital, Kathmandu, Nepal
  • Jyotshna Sapkota Assistant Professor, Department of Microbiology, Kathmandu Medical College Teaching Hospital, Kathmandu, Nepal
  • Subash Pant Assistant Professor, Department of Medicine, Kathmandu Medical College Teaching Hospital, Kathmandu, Nepal
  • Arpana Neopane Professor, Department of Medicine, Kathmandu Medical College Teaching Hospital, Kathmandu, Nepal

DOI:

https://doi.org/10.3126/jkmc.v9i4.38091

Keywords:

Antimicrobials; Bronchoalveolar lavage; Pneumonia

Abstract

Background: The common bacterial pathogens isolated from bronchoalveolar lavage (BAL) include Klebsiella pneumoniae, Acinetobacter baumanii, Pseudomonas aeruginosa and Coagulase negative Staphylococcus.

Objectives: This study was conducted to identify pneumonia causing organisms and to determine their antibiogram.

Methodology: A descriptive cross-sectional study was carried out at Kathmandu Medical College Teaching Hospital, Kathmandu, Nepal over a period of one year (Aug 2019-Jul 2020). Ethical approval (Reference Number:1004201810) was taken and convenience samplin g was done using Clinical and Laboratory Standards Institute(CLSI) guidelines. Data were analyzed using Statistical Package for Social Sciences(SPSS) version 19.

Results: Out of 32 BAL samples, 14 were culture positive. The commonest bacterial pathogens isolated were Klebsiella Pneumoniae 6(42.85%), followed by Acinetobacter baumanii 5(35.71%), Pseudomonas aeruginosa 2(14.28%) and Coagulase negative Staphylococcus 1(7.14%). The isolates were 100% sensitive to Tigecycline and Polymixin B followed by Colistin(92.85%). Cotrimoxazole was 100% resistant to these isolates followed by Azithromycin (92.85%.

Conclusion: Klebsiella pneumomiae, Acinetobacter baumanii were the most common bacterial pathogens isolated from BAL.

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Published

2020-12-31

How to Cite

Jha, B., Sharma, M., Sapkota, J., Pant, S., & Neopane, A. (2020). Antibiotic susceptibility pattern of bacterial isolates from quantitative culture of bronchoalveolar lavage fluid in patients with clinical suspicion of pneumonia. Journal of Kathmandu Medical College, 9(4), 197–200. https://doi.org/10.3126/jkmc.v9i4.38091

Issue

Vol. 9 No. 4 (2020)

Section

Original Research Articles

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