TY - JOUR AU - Shakya, Raju Prasad AU - Regmi, Sudeep AU - Adhikari, Suraj PY - 2017/12/28 Y2 - 2024/03/28 TI - Prevalence of Helicobacter Pylori among Patients undergoing Gastrodudenoscopy in a Hospital in Western Nepal JF - Journal of Lumbini Medical College JA - J. Lumbini Med. Coll. VL - 5 IS - 2 SE - Original Research Articles DO - UR - https://www.nepjol.info/index.php/JLMC/article/view/18889 SP - 69 - 73 AB - <p><span>Introduction</span>: Helicobacter pylori (<em>H. pylori</em>) related chronic gastritis is a major health problem worldwide, specially in the developing countries. The prevalence of <em>H. pylori</em> infection has been reported to vary between and even within countries. There are limited data on this infection in Western Nepal. Our objective was to study the prevalence of <em>H. pylori</em> infection and its association with presenting complains and upper gastrointestinal diseases.</p><p><span>Methods</span>: Medical records of patients undergoing gastrodudenoscopy and biopsy for various upper gastrointestinal symptoms from 1<span>st</span> of January 2015 to 30<span>th</span> of June 2017 were reviewed for presence of <em>H. pylori</em> infection, demographics, indications for gastrodudenoscopy, and histopathology findings. <em>T-test</em>, <em>Chi-square </em>test, and <em>Fisher exact</em> test were applied.</p><p><span>Results</span>: Two hundred fifty six patients (135 male and 121 female) with a mean age of 47 (<em>SD</em> = 16.5) underwent gastroscopic biopsy and had an overall <em>H. pylori</em> prevalence of 24.6%. <em>H. pylori</em> infection was most commonly noted between 41 to 60 years of age. Gender did not seem to be significantly associated (<em>p</em> = 0.82) but gastrointestinal bleed was significantly associated with <em>H. pylori</em> infection (<em>p</em> = 0.006). The most common histopathological diagnosis was gastritis followed by gastrodudenitis; however, none of the diagnosis were found to be significantly associated with <em>H. pylori</em> infection.</p><p><span>Conclusion</span>: The overall prevalence of <em>H. pylori</em> infection was 24.6% and was most common between 40 to 60 years of age. Heart burn was the most common symptom and gastrointestinal bleed was the only significantly associated symptom with <em>H. pylori</em>infection.</p> ER -