The Magical Wonders of Nitric Oxide: The Molecule of the Millennium

Authors

  • Varun Malhotra Associate Professor, department of Physiology, AIIMS, Bhopal
  • Sunil Chauhan Associate Professor, Department of Physiology, AIIMS, Bhopal
  • Santosh Wakode HOD, Department of Physiology, AIIMS, Bhopal
  • Kshitiz Upadhyay Dhungel Professor & HOD, Physiology, Janaki Medical College, Ramdaiya, Janakpur, Nepal

DOI:

https://doi.org/10.3126/jmcjms.v10i1.44636

Keywords:

eNOS, EDRF, NO

Abstract

NO is a gas and has a very short half-life (3-5s), as it is highly reactive. No  and its products are inactivated through oxidation into nitrite (NO2-) and nitrate (NO3-) Which is excreted in the urine. NO is regarded as magical molecule which has profound role in regulation of various function in various organs of human body and in health and disease. Here in this review article authors has discussed about its chemistry and metabolism, its discovery, its basic functions, role in pathophysiology of various diseases and its therapeutic implications.

 

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Published

2022-04-26

How to Cite

Malhotra, V., Chauhan, S., Wakode, S., & Upadhyay Dhungel, K. . (2022). The Magical Wonders of Nitric Oxide: The Molecule of the Millennium. Janaki Medical College Journal of Medical Science, 10(1), 61–67. https://doi.org/10.3126/jmcjms.v10i1.44636

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Review Article