TY - JOUR AU - Roy, Soumya AU - Chakrabartty, Subroto PY - 2017/10/04 Y2 - 2024/03/28 TI - Methotrexate as a Suspected Trigger of Macrophage Activation Syndrome in Juvenile Idiopathic Arthritis JF - Journal of Nepal Paediatric Society JA - J. Nepal Paedtr. Soc. VL - 37 IS - 1 SE - Case Reports DO - 10.3126/jnps.v37i1.16894 UR - https://www.nepjol.info/index.php/JNPS/article/view/16894 SP - 95-97 AB - A four year old girl with systemic onset juvenile idiopathic arthritis (SOJIA) developed macrophage activation syndrome (MAS) shortly after starting methotrexate. We observed methotrexate is a likely trigger of MAS in SOJIA. Possibly, there are only two case reports suggesting methotrexate triggered MAS. We reviewed the literature for possible mechanisms. ER -