TY - JOUR AU - Sah, Kailash Prasad AU - Rai, Ganesh Kumar AU - Shrestha, PN AU - Shrestha, Amit PY - 2010/07/13 Y2 - 2024/03/28 TI - Wilm’s Tumor: Ten Year Experience at Kanti Children’s Hospital JF - Journal of Nepal Paediatric Society JA - J. Nepal Paedtr. Soc. VL - 30 IS - 2 SE - Original Articles DO - 10.3126/jnps.v30i2.3449 UR - https://www.nepjol.info/index.php/JNPS/article/view/3449 SP - 85-89 AB - <strong>Introduction:</strong> Wilm's tumor is the second most common abdominal tumor in children. It arises from the<br />kidney. The survival of children with Wilm's tumor has improved over the past 25 years. <strong>Objectives:</strong> To<br />study the clinical presentation of Wilm&rsquo;s tumor and evaluate the ten year survival. <strong>Materials and Methods:</strong><br />A retrospective hospital based study was conducted at Kanti Children's Hospital from March 1998 to<br />February 2008. A total of 60 histopathologically diagnosed children below 14 yr of age were included in<br />the study. <strong>Results:</strong> About 2/3rd (66.5%) presented with abdominal swelling followed by abdominal pain<br />(16.5%) and fever (13.5%). A few children manifested with red colored urine (3.5%). The age of children<br />ranged from one month to 13 years with the mean age of 36 months. Males were affected more than the<br />females (M:F=3:1). Most affected age group was 2 to 5 yrs (41.5%) followed by 1 to 2 yrs (25.0%). Most<br />of the cases were in stage III (36.5%) followed by stage II (33.5%). SIOP protocol was used to treat these<br />children and overall 10 year survival rate was 50.0%. One fifth (20%) of the cases died, 16.5% relapsed<br />and 13.5% lost to follow up. <strong>Conclusion:</strong> Despite severe resource limitations, paediatric oncology unit at<br />Kanti Children&rsquo;s Hospital has been successfully treating Wilm's tumor with the success rate of 50.0%.<br /><br /><strong>Key words:</strong> Chemotherapy; Outcome; Remission; Wilm&rsquo;s tumor; SIOP.<br /><br />DOI: 10.3126/jnps.v30i2.3449<br /><br /><em>J. Nepal Paediatr. Soc.</em> May-August, 2010 Vol 30(2) 85-89 ER -