TY - JOUR AU - Kafle, Santosh Upadhyaya AU - Singh, Mrinalini AU - Kafle, Prerna Arjyal AU - KC, Bal Kumar AU - Yadav, Sanjeev Kumar AU - KC, Anadi Khatri PY - 2019/12/31 Y2 - 2024/03/29 TI - Clinico-histopathological analysis of orbito-ocular lesions: a hospital-based study JF - Journal of Patan Academy of Health Sciences JA - J Patan Acad Health Sci VL - 6 IS - 2 SE - General Section: Original Articles DO - 10.3126/jpahs.v6i2.27228 UR - https://www.nepjol.info/index.php/JPAHS/article/view/27228 SP - 39-44 AB - <p><strong>Introductions</strong>: Preoperative diagnosis of orbital and ocular lesions is necessary for optimum treatment. The study aims to analyze the histomorphological spectrum of orbito-ocular lesions and to evaluate the need of ancillary techniques for confirmation of diagnosis.</p><p><strong>Methods: </strong>A cross sectional hospital based study of orbito-ocular surgical biopsy samples obtained in the Department of Pathology, at Birat Medical College Teaching Hospital, Nepal during one-year period was analysed for clinical and histopathological findings. Demographic data, site and tissue type, benign or malignant, recommendations for special stains and immunohistochemistry panel study were analysed.</p><p><strong>Results: </strong>Out of 185 total samples, male to female ratio of 1.1:1, age ranged from ten month to 82 years, 11-20 year age group had 39 (21.1%) orbito-ocular lesions and cornea-conjunctiva was involved in 104 (56.2%). Clinical diagnosis correlated well with histopathological diagnosis, p&lt;0.001. The non-neoplastic, benign and malignant lesions were 36.7%, 33.5% and 29.7% respectively. Squamous cell carcinoma was seen in 28 (50.9%) of malignant lesions followed by sebaceous carcinoma 7 (12.7%). The special stains and immunohistochemistry panel was recommended in 38 (20.5% and 21 (11.3%) cases respectively.</p><p><strong>Conclusions: </strong>Findings suggest the clinical and histopathological diagnosis correlated well in diagnosis of a wide spectrum of orbito-ocular lesions.</p> ER -