TY - JOUR AU - Pudasaini, S AU - Prasad, KBR AU - Rauniyar, SK AU - Pathak, R AU - Pande, K AU - Koirala, S AU - Kafle, S PY - 2015/09/14 Y2 - 2024/03/29 TI - Cervical pap smear- A prospective study in a tertiary hospital JF - Journal of Pathology of Nepal JA - J Pathol Nep VL - 5 IS - 10 SE - Original Articles DO - 10.3126/jpn.v5i10.15639 UR - https://www.nepjol.info/index.php/JPN/article/view/15639 SP - 820-823 AB - <p><strong>Background: </strong>Cervical cancer is a leading cause of mortality and morbidity among women worldwide and most common gynaecological cancer in developing countries. Papanicolaou smear is a simple and cost effective screening test for cervical cancer. The aim of this study is to evaluate and interpret the cervical pap smear cytology in a tertiary hospital. The interpretation and reporting of the pap smear is based on 2001Bethesda system.</p><p><strong>Materials and methods: </strong>This is a prospective study conducted in a tertiary hospital, Nepal Medical College over a period of two and a half years (January 2013 to June 2015). All cervical pap smears received in the department of Pathology in the study period were included.</p><p><strong>Results: </strong>A total of 4160 cervical pap smears were reported in the study period. Majority of the cases were Negative for Intraepithelial lesion or malignancy (87.9%). Bacterial vaginosis, atrophy and reactive cellular changes associated with inflammation were seen in 5.3%, 2.4% and 1.5% cases respectively.   Epithelial cell abnormalities (0.5%) include Atypical squamous cells of undetermined significance, Low grade squamous intraepithelial lesion and High grade intraepithelial lesion. 88% of Low grade squamous intraepithelial lesion was seen in reproductive age group (20-45 years).<strong></strong></p><p><strong>Conclusion: </strong>Cervical cancer is the most common gynaecological cancer in the developing countries. Pap smear is the simple and cost effective screening tool to detect pre invasive cervical epithelial lesions.</p> ER -