Outcome of Lung Functions in Covid-19 Patients at a Tertiary Care Center of Eastern Nepal

Authors

  • Puru Koirala Department of Internal Medicine, Birat Medical College Teaching Hospital, Biratnagar, Nepal https://orcid.org/0000-0003-2799-5266
  • Ram Kumar Mehta Department of Internal Medicine, Birat Medical College Teaching Hospital, Biratnagar, Nepal
  • Swastik Raj Koirala Department of Internal Medicine, Birat Medical College Teaching Hospital, Biratnagar, Nepal
  • Gajendra Prasad Yadav Department of Internal Medicine, Birat Medical College Teaching Hospital, Biratnagar, Nepal
  • Surya B Parajuli Department of Community Medicine, Birat Medical College Teaching Hospital, Biratnagar, Nepal
  • Santosh Chaudhary Department of Internal Medicine, Birat Medical College Teaching Hospital, Biratnagar, Nepal

DOI:

https://doi.org/10.3126/jonmc.v12i1.56266

Keywords:

COVID-19, Lung Function Test, Pneumonia

Abstract

Background: Novel coronavirus infection has myriad clinical manifestations, such as headache, respiratory failure, and long coronavirus disease syndrome. A common cause for admission is pneumonia, and such patients have shown longer periods of respiratory symptoms and exercise intolerance after discharge. The study aimed to determine short-term and long-term lung function outcomes in coronavirus disease patients.

Materials and Methods: The prospective, cross-sectional study was conducted in coronavirus disease facility of Birat Medical College Teaching Hospital. A structured proforma including symptoms, modified medical research council dyspnea scale, 6-minute walk test and portable spirometry were recorded during 3 months follow up.

Results: A total of 58 coronavirus disease patients were admitted, 4 expired. Common symptoms were dyspnea (98.28%), fever (94.8%), dry cough (86.2%), myalgia (17.2%). Mean Forced expiratory volume in 1 second to forced vital capacity ratio was normal. The mean forced vital capacity was 46.52% at admission, 53.33% at 3 months. The mean forced expiratory flow at 25% to 75% of forced vital capacity was 56.91% at admission, 59.31% at 3 months. Mean values of forced expiratory volume predicted was 47.40% at admission, 51.69% at 3 months. Mean 6-minute walk test distance did not improve during follow-up (240.09m at 1 month, 239.35m at 3 months) and there was no improvement in oxygen saturation at 3 months compared to the first month.

Conclusion: Short-term lung function outcome demonstrated persistent dyspnea and development of mixed airways disease in all the survivors. Long-term lung function outcome observed was persistence of dyspnea, mixed airways disease, and low exercise capacity.

Downloads

Download data is not yet available.
Abstract
52
PDF
86

Author Biography

Puru Koirala, Department of Internal Medicine, Birat Medical College Teaching Hospital, Biratnagar, Nepal

Associate Professor

Downloads

Published

2023-07-17

How to Cite

Koirala, P., Mehta, R. K., Koirala, S. R., Yadav, G. P., Parajuli, S. B., & Chaudhary, S. (2023). Outcome of Lung Functions in Covid-19 Patients at a Tertiary Care Center of Eastern Nepal. Journal of Nobel Medical College, 12(1), 22–26. https://doi.org/10.3126/jonmc.v12i1.56266

Issue

Section

Original Articles