Orbital presentation of systemic vasculitis: a diagnostic and management challenge

Authors

  • M Singh Department of Ophthalmic Plastic and Reconstructive Surgery Post Graduate Institute of Medical Education and Research
  • U Singh Department of Ophthalmic Plastic and Reconstructive Surgery Post Graduate Institute of Medical Education and Research
  • Z Zadeng Department of Ophthalmic Plastic and Reconstructive Surgery Post Graduate Institute of Medical Education and Research

DOI:

https://doi.org/10.3126/nepjoph.v7i1.13173

Keywords:

Wegener’s granulomatosis, proptosis, Rituximab, management

Abstract

Background: Orbital involvement in Wegener’s Granulomatosis (WG) is rare and has an overall good prognosis.

Case: A 60-year-old hypertensive Indian female presented with vision loss and painful proptosis of left eye. Orbital incisional biopsy suggested necrotising small vessel inflammation. The saddle nose deformity and pedal nodulo- ulcerative lesions further consolidated the diagnosis of Wegener’s granulomatosis. Systemic immunosuppressant provided remission and the only relapse was managed successfully with intravenous Rituximab.

Conclusion: Wegener’s granulomatosis should be kept in the differential diagnosis of painful proptosis with a diffuse orbital mass in an elderly patient presenting with profound vision loss. Newer immune modulating agents are useful adjuncts in preventing relapses of this fatal disease.

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Published

2015-09-17

How to Cite

Singh, M., Singh, U., & Zadeng, Z. (2015). Orbital presentation of systemic vasculitis: a diagnostic and management challenge. Nepalese Journal of Ophthalmology, 7(1), 65–68. https://doi.org/10.3126/nepjoph.v7i1.13173

Issue

Vol. 7 No. 1 (2015)

Section

Case Reports

License

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