Endocannabinoid System and Ocular Vascularization

  • Raluca Iancu Emergency University Hospital, Ophthalmology Dept., Bucharest
  • Ioana-Cristina Coman Emergency University Hospital of Bucharest, Ophthalmology Dept. Bucharest http://orcid.org/0000-0002-5337-8133
  • Cosmina Barac Emergency University Hospital, Ophthalmology Dept., Bucharest
  • Mohammad Al Hammoud Braila Emergency Hospital, Ophthalmology Dept, Braila
  • Alina Popa Cherecheanu Emergency University Hospital, Ophthalmology Dept., Bucharest
Keywords: Cannabinoids, endocannabinoid system, ocular vascularisation, vasorelaxation, glaucoma

Abstract

The focus of this review is the role of endocannabinoid system in ocular and systemic circulation. By critically examining preclinical and clinical research, we explore the cannabinoid receptors localization and vascular implications as well as their interaction with other anti-inflammatory drugs. The objective is to transfer knowledge on the use of cannabinoids, specifically their effect on ocular circulation and intraocular pressure, and provide a better understanding of the endocannabinoid system complexity in modulating local and systemic circulations in order to identify potential uses and limitations of cannabinoid-based therapeutics.  

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Author Biographies

Raluca Iancu, Emergency University Hospital, Ophthalmology Dept., Bucharest

"Carol Davila" University of Medicine and Pharmacy, Faculty of Medicine, Bucharest

Ioana-Cristina Coman, Emergency University Hospital of Bucharest, Ophthalmology Dept. Bucharest

MD-24 hour shifts, phD Student

Alina Popa Cherecheanu, Emergency University Hospital, Ophthalmology Dept., Bucharest

”Carol Davila” University of Medicine and Pharmacy, Faculty of Medicine, Bucharest

Published
2018-12-31
How to Cite
Iancu, R., Coman, I.-C., Barac, C., Al Hammoud, M., & Popa Cherecheanu, A. (2018). Endocannabinoid System and Ocular Vascularization. Nepalese Journal of Ophthalmology, 10(2), 168-175. https://doi.org/10.3126/nepjoph.v10i2.20464
Section
Review Article