Influence of Glycated Haemoglobin Levels on Intraocular Pressure in patients with Type –II Diabetes Mellitus

  • Ajai Agrawal Department of Ophthalmology, All India Institute of Medical Sciences, Rishikesh
  • Shubham Ahuja Department of Ophthalmology, All India Institute of Medical Sciences, Rishikesh
  • Anupam Singh Department of Ophthalmology, All India Institute of Medical Sciences, Rishikesh
  • Ramanuj Samanta Department of Ophthalmology, All India Institute of Medical Sciences, Rishikesh
  • Sanjeev Kumar Mittal Department of Ophthalmology, All India Institute of Medical Sciences, Rishikesh
Keywords: Glycated haemoglobin, Intra ocular pressure, Type 2 diabetes mellitus

Abstract

Introduction: Patients with diabetes mellitus are at a higher risk of developing primary open angle glaucoma (POAG) as compared to non-diabetic patients.

Objectives: To determine whether there is a correlation between hyperglycemic levels and intraocular pressure (IOP) and to identify patients of Type II diabetes mellitus who are at a higher risk of developing glaucoma.

Materials and Methods: This was a hospital based, cross sectional study performed on patients with type II diabetes mellitus, at a tertiary health care center in Uttarakhand, India between July, 2018 and September, 2018. 318 eyes of 159 patients with Type2 diabetes mellitus were included in the study. IOP was measured by Goldmannappla nation to no meter and central corneal thickness was measured with specula microscope in all patients, in addition to glycated hemoglobin levels (HbA1c) and fasting and post-prandial blood glucose levels. The data was analysed using SPSS 22 software.

Results: Mean IOP was found to be 15.75 ± 3.18 mm Hg in patients with HbA1c levels between 6.5%-12% (Group I) and 17.42 ± 2.67 mm Hg in patients with HbA1c levels more than 12 % (Group II). The difference between the two groups was statistically significant (P =0.013). Out of 159 patients with Type 2 Diabetes mellitus, a total of 11 patients had IOP more than 21mm Hg in one or both the eyes.

Conclusion: Hyperglycaemic levels as determined by raised HbA1c levels are associated with higher intraocular pressures in patients with type 2 diabetes mellitus.

Downloads

Download data is not yet available.
Abstract
158
pdf
154
Published
2019-09-02
How to Cite
Agrawal, A., Ahuja, S., Singh, A., Samanta, R., & Mittal, S. (2019). Influence of Glycated Haemoglobin Levels on Intraocular Pressure in patients with Type –II Diabetes Mellitus. Nepalese Journal of Ophthalmology, 11(1), 19-23. https://doi.org/10.3126/nepjoph.v11i1.25412
Section
Original Articles