TY - JOUR AU - Raut, Roshan AU - KC, Man Bahadur AU - Rajbhandari, Sujeeb AU - Dhungana, Murari AU - Sharma, Mukunda AU - Joshi, Surakshya AU - Bajracharya, Prashant PY - 2019/11/14 Y2 - 2024/03/28 TI - Cardiac Resynchronization Therapy- Single center experience in Nepal JF - Nepalese Heart Journal JA - Nepalese Heart J. VL - 16 IS - 2 SE - Original Articles DO - 10.3126/njh.v16i2.26308 UR - https://www.nepjol.info/index.php/NHJ/article/view/26308 SP - 5-9 AB - <p><strong>Background and Aims:</strong> Cardiac resynchronization therapy (CRT) has become an established treatment modality for&nbsp;patients with advanced heart failure. CRT abbreviates the dysynchronus heart failure mainly by correcting left ventricular&nbsp;dysynchrony. In the last three years, CRT has been regularly done in Shahid Gangalal National Heart Center(SGNHC) which&nbsp;has provided us the platform to report the outcome of CRT, for the first time in Nepal. The aim of this study is to review the&nbsp;recent clinical experience and outcome of CRT in our centre.</p><p><strong>Methods:</strong> All consecutive patients who underwent CRT at SGNHC from July, 2016 to July, 2019 were reviewed retrospectively.</p><p><strong>Results:</strong> Altogether 42 patients underwent CRT. Mean age was 65±11 years (range 43 to 84). Coronary sinus cannulation&nbsp;was successful in 41 patients. In one patient, LV lead delivery was unsuccessful. Thus, procedural success was obtained in&nbsp;95% (40 out of 42) patients. LV lead dislodgement occurred in three patients (7%). Coronary sinus dissection occurred in&nbsp;two patients (5%). Biventricular (BiV) paced QRS was significantly narrower compared to baseline QRS (127ms Vs 162ms,&nbsp;p&lt;0.01). During mean follow up of 12±10 months (range 1 to 30 months), there was significant improvement in the clinical&nbsp;outcomes: NYHA class (1.8 Vs 2.9, p&lt;0.01), LVEF (22.3 Vs 27.5, p&lt;0.01), left ventricle internal diameter in systole (LVIDs),&nbsp;(57 Vs 60.5 mm, p&lt;0.01). The CRT responder rate was 86%. Super-responder was observed in 12% of patients.</p><p><strong>Conclusion:</strong> In SGNHC, Cardiac resynchronization therapy is emerging as a routine treatment strategy with a reasonable&nbsp;efficacy and safety outcome.</p> ER -