Patch Testing In Nepalese Population: A Single Center Study From Kathmandu, Nepal

  • Sushil Paudel Civil Service Hospital, Kathmandu
  • Guma Pun Civil Service Hospital, Kathmandu
  • Niraj Parajuli National Academy of Medical Sciences, Kathmadu
  • Rabindra Sharma Civil Service Hospital, Kathmandu
Keywords: Allergens, Dermatitis, Allergic Contact, Eczema, Nickel sulfate

Abstract

Introduction: Patch testing is a diagnostic tool used in investigation to identify specific allergens in allergic contact dermatitis (ACD). It helps find the prevalence and the trends of contact sensitization in the community.

Objective: To report the two year patch test results from a central hospital in Kathmandu.

Materials and Methods: Consecutive consenting patients of suspected ACD were patch tested with an Indian standard Series (Systopic) from June 2014 to August 2016.

Results: Out of 141 patients tested, 89 were female (63.12%) and 52 were male (36.88%). Hand eczema was the commonest pattern (53 patients) followed by persistent and recurrent eczema (44 patients) and face eczema (25 patients). Fifty- five patients (39%) had at least 1 positive allergic reaction. Among these, 16.31% were male and 22.70% were female. The most common allergen was nickel sulfate (19.9%) followed by fragrance mix (7.8%) and paraphenyldiamine (PPD) (6.4%). Out of total positive cases 27 (21 females and 6 males) had shown strong positive reactions (++). The Nickel Sulfate was responsible in majority of cases (18/27 cases). Farmers had the highest (57.14%) rate of positive allergic reactions followed by housewives (39.62%). According to the regional eczema, patients with persistent and recurrent eczema of different parts of body had the highest rate of positive allergic reactions (47.72%). Almost half of patient with facial eczema (40%) had positive patch test.

Conclusion: Larger studies are required in the different parts of the country to find a more accurate data regarding the sensitization pattern in Nepalese population.

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Author Biographies

Sushil Paudel, Civil Service Hospital, Kathmandu

Registrar, Department of Dermatology

Guma Pun, Civil Service Hospital, Kathmandu

Registrar, Department of Dermatology

Niraj Parajuli, National Academy of Medical Sciences, Kathmadu

Assistant Professor, Department of Dermatology

Rabindra Sharma, Civil Service Hospital, Kathmandu

Registrar, Department of Dermatology

Published
2019-03-31
How to Cite
Paudel, S., Pun, G., Parajuli, N., & Sharma, R. (2019). Patch Testing In Nepalese Population: A Single Center Study From Kathmandu, Nepal. Nepal Journal of Dermatology, Venereology & Leprology, 17(1), 12-16. https://doi.org/10.3126/njdvl.v17i1.23118
Section
Original Articles