Mycosis Fungoides: A Case Report

  • Anisha Joshi Department of Dermatology, Nepal Medical College and Teaching Hospital, Kathmandu, Nepal https://orcid.org/0000-0001-8316-3259
  • Deeptara Pathak Thapa Department of Dermatology, Nepal Medical College and Teaching Hospital, Kathmandu, Nepal
Keywords: Histopathology, Immunohistochemistry, Mycosis Fungoides

Abstract

Mycosis fungoides is the most common primary cutaneous T-cell lymphoma and is recognized as one of the rare malignant skin neoplasms. Hypopigmented mycosis fungoides is a variant of mycosis fungoides, described in dark-skinned individual and Asian patients.  We report a case of 32 years old Nepalese female who had presented with multiple asymptomatic hypopigmented macules over the bilateral arms, thighs, abdomen, back of trunk and buttocks. Skin biopsy revealed few atypical cells (small/medium-sized, cerebriform nuclei with halo) confined to epidermis with epidermotropism. Immunohistochemistry showed CD3, CD4, CD5 and CD8 positivity. The patient was managed with topical steroids, oral methotrexate and phototherapy, and she is on regular follow up. As the disease has an indolent clinical course, long term follow up is necessary.

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Author Biographies

Anisha Joshi, Department of Dermatology, Nepal Medical College and Teaching Hospital, Kathmandu, Nepal

Resident, Department of Dermatology, Nepal Medical College, Kathmandu, Nepal

Deeptara Pathak Thapa, Department of Dermatology, Nepal Medical College and Teaching Hospital, Kathmandu, Nepal

Associate Professor, Department of Dermatology, Nepal Medical College and Teaching Hospital, Kathmandu , Nepal

Published
2021-04-02
How to Cite
Joshi, A., & Pathak Thapa, D. (2021). Mycosis Fungoides: A Case Report. Nepal Journal of Dermatology, Venereology & Leprology, 19(1), 60-64. https://doi.org/10.3126/njdvl.v19i1.34167
Section
Case Reports