Dual Threat: Neurosyphilis and Congenital Syphilis in a 3-Month-Old Infant

Pooja Gupta; Laxman Chapagain; Ashu Sharma; Manisha Gartaula; Gunawati Chaulagain; Upama Paudel

doi:10.3126/njdvl.v24i1.84136

Authors

Pooja Gupta Maharajgunj Medical Campus, Institute of Medicine. https://orcid.org/0009-0008-8377-236X
Laxman Chapagain Maharajgunj Medical Campus, Institute of Medicine. https://orcid.org/0009-0001-5906-4311
Ashu Sharma Maharajgunj Medical Campus, Institute of Medicine. https://orcid.org/0009-0000-3414-1686
Manisha Gartaula Maharajgunj Medical Campus, Institute of Medicine. https://orcid.org/0009-0004-6196-7052
Gunawati Chaulagain Maharajgunj Medical Campus, Institute of Medicine.
Upama Paudel Maharajgunj Medical Campus, Institute of Medicine. https://orcid.org/0000-0002-5695-4247

DOI:

https://doi.org/10.3126/njdvl.v24i1.84136

Keywords:

Congenital Syphilis, Maternal Syphilis, Neurosyphilis

Abstract

Congenital syphilis is a result of mother-to-child transmission (MTCT) of syphilis during pregnancy. The outcomes of MTCT may range from an array of clinical manifestations to serious consequences like perinatal mortality due to miscarriage, stillbirth, and neonatal death and an increased risk of preterm and low-birthweight infants. Neurosyphilis is supposed to occur in as high as 60% cases of congenital syphilis, diagnosed based on various cerebrospinal fluid abnormalities, however, this is underreported. Maternal screening and treatment for syphilis during pregnancy remains cornerstone of congenital syphilis prevention. We report a case of congenital syphilis with neurosyphilis in a 3-month-old boy, born to a 20-year-old mother who never attended antenatal services

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