Cutaneous Mosaicism Along Blaschko Lines: A Case Series of Epidermal Verrucous Nevus and Linear Whorled Nevoid Hypermelanosis
Keywords:
Blaschko lines, Cutaneous mosaicism, Epidermal verrucous nevus, Linear and whorled nevoid hypermelanosis, Linear dermatoses, Somatic mutationsAbstract
Cutaneous mosaicisms are often seen along Blaschko lines. These lines represent ectodermal cell migration. Lesions derived from epidermal components typically follow Blaschko line patterns. Here, we present three cases of linear dermatoses along the Blaschko lines. Two cases of linear epidermal verrucous nevus and one case of linear and whorled nevoid hypermelanosis. Two cases are histologically confirmed. All three of our patients had normal development, and no systemic abnormalities were detected. Epidermal verrucous nevus and Linear whorled nevoid hypermelanosis are two conditions that arise from mosaicism, causing a clone of skin cells with an increased ability to produce pigment. Early clinical and histopathological diagnosis is essential. Most patients may seek treatment due to a poor cosmetic appearance.
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