Comparative Study of Rectal Misoprostol to Oxytocin Infusion in Preventing Postpartum Haemorrhage After Caesarean Section

Authors

  • AI Adanikin Department of Obstetrics and Gynaecology, Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife
  • E Orji Department of Obstetrics and Gynaecology, Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife
  • PO Adanikin Health Centre, Obafemi Awolowo University, Ile-Ife
  • O Olaniyan Department of Obstetrics and Gynaecology, Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife

Keywords:

caesarean section, misoprostol, oxytocin infusion, postpartum haemorrhage

Abstract

Aims: This comparative study aimed to compare the efficacy of rectal misoprostol to oxytocin infusion in preventing primary postpartum haemorrhage after caesarean section.

Methods: Fifty pregnant women with identifiable risk factors for post-partum haemorrhage who delivered baby by caesarean section were randomized to receive 600 μg rectal misoprostol and a placebo infusion intravenously or placebo rectally and a 20 iu oxytocin infusion. Post-operative blood loss four hours after surgery was estimated by application of pads of known weight.

Results: The mean immediate four hours post-operative blood loss was not significantly different between the rectal misoprostol and oxytocin infusion group (100.08 ± 24.85 ml versus 108.20 ± 29.93 ml; p =0.144) and the change between the pre-operative and post-operative hematocrit was similar.

Conclusions: Post-caesarean section rectal misoprostol has comparative efficacy to oxytocin infusion in preventing post-partum haemorrhage. It is recommended for use as alternative uterotonic in settings where there is low refrigeration capacity.

Nepal Journal of Obstetrics and Gynaecology / Vol 8 / No. 2 / Issue 16 / July-Dec, 2013 / 34-37

DOI: http://dx.doi.org/10.3126/njog.v8i2.9767

Downloads

Download data is not yet available.
Abstract
790
PDF
919

Downloads

Published

2014-02-06

How to Cite

Adanikin, A., Orji, E., Adanikin, P., & Olaniyan, O. (2014). Comparative Study of Rectal Misoprostol to Oxytocin Infusion in Preventing Postpartum Haemorrhage After Caesarean Section. Nepal Journal of Obstetrics and Gynaecology, 8(2), 34–37. Retrieved from https://www.nepjol.info/index.php/NJOG/article/view/9767

Issue

Vol. 8 No. 2 (2013)

Section

Original Articles

License

Copyright on any research article in the Nepal Journal of Obstetrics and Gynaecology is retained by the author(s).

The authors grant the Nepal Journal of Obstetrics and Gynaecology a license to publish the article and identify itself as the original publisher.

Articles in the Nepal Journal of Obstetrics and Gynaecology are Open Access articles published under the Creative Commons CC BY-NC License (https://creativecommons.org/licenses/by-nc/4.0/)

This license permits use, distribution and reproduction in any medium, provided the original work is properly cited, and it is not used for commercial purposes.