Undetectable TSH could be a TSH variant; case of a young asymptomatic Nepalese male

  • Santosh Pradhan Samyak Diagnostic; Jawalakhel, Lalitpur, Nepal
  • Vivek Pant Samyak Diagnostic; Jawalakhel, Lalitpur, Nepal
  • Keyoor Gautam Samyak Diagnostic; Jawalakhel, Lalitpur, Nepal
  • Devish Pyakurel Samyak Diagnostic; Jawalakhel, Lalitpur, Nepal
  • Abha Shrestha Samyak Diagnostic; Jawalakhel, Lalitpur, Nepal
Keywords: Thyroid stimulating hormone, TSH, TSH variant, Immunoassay

Abstract

Thyroid function tests are frequently ordered test. Infrequently, the automated thyroid hormone assay system is subjected to interference which may yield false results, thus leading to inappropriate diagnosis and management. We report an unusual case of clinically misdiagnosed subclinical hyperthyroidism with undetectable TSH due to negative interference in particular TSH assay platforms in a young Nepalese male.

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Author Biographies

Santosh Pradhan, Samyak Diagnostic; Jawalakhel, Lalitpur, Nepal

Department of Clinical Biochemistry

Vivek Pant, Samyak Diagnostic; Jawalakhel, Lalitpur, Nepal

Department of Clinical Biochemistry

Keyoor Gautam, Samyak Diagnostic; Jawalakhel, Lalitpur, Nepal

Department of Pathology

Devish Pyakurel, Samyak Diagnostic; Jawalakhel, Lalitpur, Nepal

Department of Pathology

Abha Shrestha, Samyak Diagnostic; Jawalakhel, Lalitpur, Nepal

Department of Pathology

Published
2019-05-14
How to Cite
Pradhan, S., Pant, V., Gautam, K., Pyakurel, D., & Shrestha, A. (2019). Undetectable TSH could be a TSH variant; case of a young asymptomatic Nepalese male. Journal of Diabetes and Endocrinology Association of Nepal, 3(1), 34-37. https://doi.org/10.3126/jdean.v3i1.24071
Section
Case Reports