@article{Piya_Gurung_Khatri_2019, title={Thyroid function status in patients with thyroid associated ophthalmopathy: a study for Nepal}, volume={3}, url={https://www.nepjol.info/index.php/jdean/article/view/24058}, DOI={10.3126/jdean.v3i1.24058}, abstractNote={<p><strong>Introduction:</strong> Thyroid Eye Disease (TED) is an organ-specific autoimmune inflammatory incapacitating eye disorder usually associated with Graves’ disease affecting the orbit. Objectives: To determine thyroid function status in patients with thyroid-associated Ophthalmopathy.</p> <p><strong>Methods:</strong> This is a hospital-based cross-sectional study of sixty three clinically diagnosed new cases of thyroid-associated ophthalmopathy done at Nepal Eye Hospital, Kathmandu from February 2012 to January 2013. Detailed history, systemic & ocular examination with special emphasis on evaluation of extraocular movement, lid signs, exophthalmos with Hertel’s exophthalmometer was done. Thyroid function test and endocrine consultation were also done in all cases.</p> <p><strong>Results:</strong> There were an equal distribution of TED with hyperthyroid (34.95%) and euthyroid status (34.95%). The most common presentation of both euthyroid and hypothyroid patient was tremor (13.4%) and palpitation (13.45%). The most common symptom of TED was foreign body sensation (54 %) but in TED with euthyroid and hypothyroid status, redness (22.2 %) and diminution of vision (20.6 %) were more frequent symptoms respectively. The most common presenting sign was Von Graefe’s sign (69 %). Among TED with hyperthyroid and hypothyroid status, Dalrymple’s sign (29.3%) and Mobius sign (17.4%) were most common respectively.</p> <p><strong>Conclusion:</strong> Thyroid-associated ophthalmopathy is an important health concern among patients with a thyroid disorder. TED with hyperthyroid states present more severely than hypothyroid and euthyroid states. As TED occurred with a high prevalence in all thyroid states, a close collaboration between endocrinologists and ophthalmologists along with timely referrals of patients with any eye complaint is mandated.</p>}, number={1}, journal={Journal of Diabetes and Endocrinology Association of Nepal}, author={Piya, Saurav and Gurung, Jeena and Khatri, Anadi}, year={2019}, month={May}, pages={3–9} }