Problems and Solution to Diagnose Extrapulmonary Tuberculosis in Central Region of Nepal

Authors

  • Ravi Shankar Gupta Department of Microbiology, National Medical College, Birgunj
  • Tarannum Khatun Department of Obstetrics & Gynecology, National Medical College, Birgunj
  • Akhtar Alam Ansari Department of Pharmacology, National Medical College, Birgunj
  • Amrullah Shidiki Department of Microbiology, National Medical College, Birgunj
  • Dipak Bhargava Department of Microbiology, National Medical College, Birgunj
  • Bidhya Gupta National Medical College Nursing Campus, Birgunj
  • Anirban Majumder Department of Physiology, National Medical College, Birgunj

DOI:

https://doi.org/10.3126/medphoenix.v1i1.17888

Keywords:

Extrapulmonary, Nepal, Polymerase chain reaction, Tuberculosis

Abstract

Extrapulmonary Tuberculosis is high, challenging the clinicians to make correct diagnosis. Microscopy, culture and fine needle aspiration cytology have their limitations in regard to specificity and sensitivity. In this report, polymerase chain reaction is used for detecting and distinguishing Extrapulmonary Tuberculosis. A case of retropharyngeal abscess was selected from which pus was collected which was negative for microscopy and culture in routine microbiology as well as mycobacteriology. Cytopathological examination was also negative. Polymerase chain reaction was applied to detect Mycobacterium tuberculosis specific IS6110 gene. The patients responded with anti-tuberculosis treatment well. Polymerase chain reaction was introduced for diagnosis of Extrapulmonary Tuberculosis since it can be done within hours, monitor therapy and also differentiate Mycobacterium tuberculosis from other Mycobacterial species.

MED Phoenix

 Volume (1), Issue (1) July 2016, page: 41-43

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Published

2017-07-31

How to Cite

Gupta, R. S., Khatun, T., Ansari, A. A., Shidiki, A., Bhargava, D., Gupta, B., & Majumder, A. (2017). Problems and Solution to Diagnose Extrapulmonary Tuberculosis in Central Region of Nepal. Med Phoenix, 1(1), 41–43. https://doi.org/10.3126/medphoenix.v1i1.17888

Issue

Section

Case Reports