Nepal Medical College Journal https://www.nepjol.info/index.php/nmcj <p>Nepal Medical College Journal is the official journal of Nepal Medical College Pvt. Ltd (NMC), Attarkhel, Gokarneshwor Municipality-8, Kathmandu, Nepal. P.O. Box 13344, Phone: +977 01 4911008 &nbsp;| &nbsp;4912118 &nbsp;| Extension 607, Email: <a href="mailto:nmcjournal@nmcth.edu">nmcjournal@nmcth.edu</a>.</p> <p>It is also available on its own website <a href="http://jnmcth.nmcth.edu/index.php" target="_blank" rel="noopener">http://jnmcth.nmcth.edu/index.php</a></p> en-US nmcjournal@nmcth.edu (Prof. Dr. Shiba Kumar Rai) sioux.cumming@ubiquitypress.com (Sioux Cumming) Mon, 27 Jun 2022 10:29:43 +0000 OJS 3.3.0.6 http://blogs.law.harvard.edu/tech/rss 60 Knowledge regarding obstetric danger signs among mother attending antenatal clinic at Scheer Memorial Adventist Hospital, Banepa, Kavre https://www.nepjol.info/index.php/nmcj/article/view/46016 <p>Knowledge about obstetric danger signs is very crucial for preventing obsterric complication. Globally there was 211 maternal deaths per 1,00,000 live birth in 2017. The maternal mortality ratio for Nepal is 239 deaths per 1,00,000 live births in 2016. A descriptive cross sectional study was conducted to assess the knowledge regarding obstetric danger signs among pregnant mother attending ANC at Scheer Memorial Adventist Hospital, Banepa, Kavre, Nepal. Total 100 respondents were selected using non probability purposive sampling technique through a semi-structured interview questionnaire. Data were analyzed in SPSS-16 using descriptive statistics (mean, frequency, standard deviation and percentage) and inferential statistic Chi Square. The study shows that mean age of the respondents was 25.56±4.307. More than half of the respondents (53%) were from 15-25 age group. Majority of respondent (97%) were literate. Fifty six percent of respondents had adequate knowledge on obstetric danger signs, while 27% of respondents had moderate knowledge and few respondents (17%) had inadequate knowledge. There is no any significant relationship with knowledge with selected variable age, educational status, gravida, week of gestation and -number of ANC visit. Thus it is concluded about that the entire pregnant mother requires some interventions for the awareness regarding obstetric danger signs from the beginning of ANC visit. ANC visit should be focused more than eight times as recommended by WHO.</p> Nirmala Manandhar, Manita Tamang Copyright (c) 2022 Nepal Medical College Journal http://creativecommons.org/licenses/by/4.0 https://www.nepjol.info/index.php/nmcj/article/view/46016 Mon, 27 Jun 2022 00:00:00 +0000 Cardiovascular reactivity to stress shows proneness to future blood pressure status in students of a teaching hospital in Nepal https://www.nepjol.info/index.php/nmcj/article/view/46018 <p>Stress is a condition that disrupts or threatens to disrupt homeostasis. Stress may be physical or mental. Physical stress includes exercise (isometric or isotonic), pain, temperature (too hot or cold) etc. The development of hypertension is usually preceded by a prehypertensive state that may be manifested by abnormal cardiovascular reactivity to different types of stress viz., mental stress, cold water immersion, isotonic exercise, isometric handgrip, and valsalva maneuver. In present study, we have used isometric handgrip (IHG) exercise, as a stressor, aiming to identify individuals at increased risk for developing hypertension at early life. Normotensive, non-smoker sedentary two hundred male subjects, one hundred each from normotensive and hypertensive families, of age group 18-25 years participated in the study as volunteers. The causal blood pressure and heart rate of the participants were recorded in the sitting position by using mercury sphygmomanometer and stethoscope. Then, the isometric handgrip (IHG) exercise demonstrated to each of them using handgrip dynamometer. Maximum voluntary contraction (MVC) was noted as maximum pressure (in Kg) sustained during three seconds of handgrip using a handgrip dynamometer. The participants were asked to sustain isometric handgrip at one third of MVC for one minute with the same instrument (handgrip dynamometer). Both blood pressure and heart rate were recorded immediately after 1 and 3 minutes following isometric handgrip (IHG) exercise. The data analyzed using t-test showed that diastolic blood pressure didn’t return and stabilized to pre-exercise level even after 3 minutes following exercise in volunteers who were mostly from hypertensive family. More number of volunteers with family history of hypertensive (24%) showed elevated diastolic blood pressure even after 3 minutes whereas a few of the volunteers (8%) with no family history of hypertension showed rise in DBP even after 3 minutes following isometric handgrip (IHG) exercise. This present study indicated that the individuals having family history of hypertension are prone to develop hypertension in their early life, therefore, must adopt the healthier life style like avoidance of alcohol, smoking, and practice yogic exercise.</p> Smriti Singh, Rajan Pandit, Barsika Katwal Copyright (c) 2022 Nepal Medical College Journal http://creativecommons.org/licenses/by/4.0 https://www.nepjol.info/index.php/nmcj/article/view/46018 Mon, 27 Jun 2022 00:00:00 +0000 Medication adherence among chronic obstructive pulmonary disease patients: an interventional study in a tertiary care hospital of Nepal https://www.nepjol.info/index.php/nmcj/article/view/46021 <p>Chronic Obstructive Pulmonary Disease (COPD) is a significant health problem, associated with mortality and morbidities. Low medication adherence is common in patients with COPD. The primary purpose of this study was to evaluate medication adherence after educational intervention was provided to COPD patients. In this interventional study, conducted at a tertiary care center of Nepal from July 2019 to December 2019, a total of 114 patients were divided randomly into two groups: intervention group (patients who received an educational intervention) and control group (patients who received no educational intervention) by using simple randomization technique. The outcomes of educational intervention are then compared between the intervention group and the control group with the aid of the leaflet. A structured questionnaire and the pre-validated Self-Administered Medication Adherence Questionnaire were used to collect information like demographic details and medication adherence. Data were entered and analyzed using SPSS-20 program. Out of 114 patients, only 93 patients came for follow-up after one month. There was a significant improvement in the medication adherence scale score in the intervention group compared to the control group (p &lt;0.05) and the level of adherence was found to be high in the intervention group after one-month follow-up. The major reasons for medication non-adherence were financial problems and symptomatic relief in both groups. This study showed that educational intervention among COPD patients plays an essential role in improving medication adherence through proper counseling about their disease and its maintenance.</p> Anita Yadav, Najma Khatun, Pradip Chhetri Copyright (c) 2022 Nepal Medical College Journal http://creativecommons.org/licenses/by/4.0 https://www.nepjol.info/index.php/nmcj/article/view/46021 Mon, 27 Jun 2022 00:00:00 +0000 Study on adverse effects of COVISHIELD vaccine among hospital employees of Nepal Medical College and Teaching Hospital https://www.nepjol.info/index.php/nmcj/article/view/46024 <p>Nepal government provided COVISHIELD vaccine first to the hospital employees and other front liners in January 2021. The objective of our study was to observe the adverse effects of the COVISHIELD among hospital employees of Nepal Medical College and Teaching Hospital (NMCTH). This was a descriptive cross-sectional study conducted from March to August 2021. The study was commenced after obtaining ethical clearance from the Institutional Review Committee of NMCTH. Self-reported socio-demographic details and symptomatic adverse effects reported after the first and second dose of COVISHIELD were noted. The data were entered in SPSS 16 and analysed. Out of 436 participants, 360 (82.6%) and 243 (55.7%) had reported adverse effects after the first and second dose of the COVISHIELD respectively. The adverse effects reported following COVISHIELD were common and predictable.</p> Lujaw Ratna Tuladhar, Anju Khapung, Nishchal Dhakal, Deepak Regmi, Abja Sapkota, Jyotsana Pokharel Copyright (c) 2022 Nepal Medical College Journal http://creativecommons.org/licenses/by/4.0 https://www.nepjol.info/index.php/nmcj/article/view/46024 Mon, 27 Jun 2022 00:00:00 +0000 Prevalence of malnutrition among under-five children residing in Kamal Gaupalika, Jhapa https://www.nepjol.info/index.php/nmcj/article/view/46025 <p>Malnutrition among under-five is a major global health problem in developing countries like Nepal. It directly or indirectly affects many aspects of the child’s health, adversely affecting growth and development. Also, malnutrition affects the child’s ability to learn and process information and growth. This study assesses the prevalence of malnutrition among under-five children in Kamal Gaupalika, Jhapa, Nepal. First, a descriptive cross-sectional method was conducted among 60 under-five children and their mothers. The interview included semi-structured and structured questionnaires regarding socio-demographic and contributing factors of malnutrition and anthropometric measurement (analog weighing machine, measuring tape, mid-upper arm circumference) used for data collection. Then, the collected data were analyzed using SPSS-16, employing descriptive statistics (i.e. percentage, frequency, mean and standard deviation) and inferential statistics (i.e. chi-square). This study shows that 41.67% were malnourished. Among them, stunting was 20.0%, wasting was 25.0%, and underweight was 31.7%. Anthropometric measurement showed 83.3% were well-nourished, 11.7% were at risk for acute malnutrition, and 5% were moderate acute malnutrition. Family income was found to be significantly associated with malnutrition (stunting p = 0.001, wasting p = 0.007 and underweight p = 0.000). In contrast, there was no association in age, gender, ethnicity, mother’s education, father’s education, and mother’s age at childbirth. Our results showed that malnutrition is prevalent in the selected study area. Therefore, community-based nutrition awareness and education programs are necessary to improve the nutritional status of children.</p> Babita Kayastha, Soniya Rai, Dibyashwori Lakhe, Rubi Pradhan, Sapana Sainju Copyright (c) 2022 Nepal Medical College Journal http://creativecommons.org/licenses/by/4.0 https://www.nepjol.info/index.php/nmcj/article/view/46025 Mon, 27 Jun 2022 00:00:00 +0000 Prevalence of intestinal parasitic infection among school children in Kirtipur Municipality, Kathmandu https://www.nepjol.info/index.php/nmcj/article/view/46027 <p>Intestinal parasitic infections are a major cause of morbidity in developing countries including Nepal. Most common intestinal parasites reported in Nepal are <em>Ascaris lumbricoides</em>, <em>Hymenolepis nana</em>, Hookworm, <em>Trichuris trichiura</em>, <em>Giardia lamblia </em>and <em>Entamoeba histolytica</em>. This study aimed to find out the prevalence of various intestinal parasitic infections among school children in Kirtipur Municipality, Kathmandu. A cross-sectional observational study was carried out with prepared questionnaire and stool examination between October to November, 2021. Altogether, 409 stool samples were randomly collected from different schools and examined by direct smear method. Out of 409 stool samples, 73 (17.8%) were positive and 336 (82.1%) were negative. Among positive cases, helminthic infection was seen in 45 (11.0%) and protozoan infection was found in 28 (6.8%). Altogether eight species of intestinal parasites were detected, the most common was <em>A. lumbricoides </em>(34.2%), followed by protozoa <em>G. lamblia </em>(23.3%), <em>E. histolytica </em>(15.1%), <em>T. trichiura </em>(10.96%), Hookworm (6.8%), <em>Enterobius vermicularis </em>(4.11%), <em>Taenia solium </em>(4.11%) and <em>H. nana </em>(1.37%) respectively. Study showed that, there was 63 (86.30%) single infections, 9 (12.33%) double infections and 1 (1.37%) multiple infection. The present study reveals that intestinal parasites are abundant among students of Kirtipur Municipality, Kathmandu. The situation strongly calls for the use of control measures including treatment of infected individuals, improvement of health status of infected students by health education, public health awareness and also develop the health care facilities and aware the people for the utilization of health services.</p> Amulya Dahal, Dev Bahadur Roka, Shiv Mangal Prasad, Srishti Shrestha Copyright (c) 2022 Nepal Medical College Journal http://creativecommons.org/licenses/by/4.0 https://www.nepjol.info/index.php/nmcj/article/view/46027 Mon, 27 Jun 2022 00:00:00 +0000 Study of variations in origin and course of cystic artery in relation to Calot’s triangle https://www.nepjol.info/index.php/nmcj/article/view/46028 <p>Calot’s triangle is an anatomical space and also known as “triangle of cholecystectomy”. It is bounded medially by Common hepatic duct, laterally by cystic duct, and superiorly by the under surface of liver and its main contain is Cystic artery. The variation in the origin and course of the cystic artery can cause serious problems resulting, severe arterial bleeding during any surgical procedures. Hence, variations in the Calot’s triangle are very important for the surgeons. An observational cross sectional study was carried out in Department of Anatomy of two Medical Colleges in Kathmandu, Nepal. A total of 30 embalmed human cadavers were dissected, in 27 cases (90.0%), cystic artery arose from right hepatic arteries, the mean length was 11.47 mm. One (3.3%) cystic artery arose from proper hepatic artery, one (3.3%) from superior mesenteric artery and one (3.3%) from accessory hepatic artery and the length of the cystic arteries were found to be measured as 15.88 mm, 27.49 mm and 24.17 mm respectively. The cystic artery was also found to be lying inside and outside the Calot‘s triangle in 96.7% and 3.3% respectively. In 26 cases (86.7%) cystic arteries were observed as passing posterior to the common hepatic duct. Further in 2 cases (6.7%) cystic arteries were found to be lying anterior to the common hepatic duct. Result also showed as in 1 case (3.3%) it was running anterior to the bile duct and in 1 case (3.3%) between right and left hepatic ducts. In conclusion the variations in the origin and course of the cystic artery are essential in performing cholecystectomy (open or laparoscopic).</p> Allin Pradhan, Chhiring Palmu Lama, Shaligram Dhungel Copyright (c) 2022 Nepal Medical College Journal http://creativecommons.org/licenses/by/4.0 https://www.nepjol.info/index.php/nmcj/article/view/46028 Mon, 27 Jun 2022 00:00:00 +0000 Knowledge regarding obstetric danger signs among pregnant women https://www.nepjol.info/index.php/nmcj/article/view/46029 <p>Knowledge of obstetric danger signs is crucial to reduce maternal morbidity and mortality by identifying the problems earlier and avoiding the delay in seeking obstetric care. According to World Health Organization (WHO) more than 70% of maternal deaths occur due to obstetric complications and most of these deaths occur in developing countries. Most of these are preventable if pregnant women can identify these life-threatening danger signs on time and seek appropriate emergency obstetric care. This study was conducted to assess the knowledge of obstetric danger signs among pregnant women. A descriptive cross-sectional study was carried out from 15th July to 30th August 2021, 194 pregnant women who visited the Gynaecology Outpatient Department in Nepal Medical College Teaching Hospital, were enrolled for the study. Data were collected through face to face interviews using a structured questionnaire. The study findings revealed that overall knowledge on obstetric danger signs was suboptimal (3.1%). The median knowledge score of respondents on antenatal danger signs was 30.0% (Q1-Q3=17.5-40), intra-natal danger signs was 0.0% (Q1-Q3=0-20) and postnatal danger signs were 25% (Q1-Q3=0- 25). Severe vaginal bleeding was the most frequently mentioned danger sign in each of the three gestational periods (antenatal: 78.9%, intra-natal; 29.9% and postnatal; 39.7%). In conclusion, service providers and health management teams should emphasize on information, education and communication for every pregnant woman focusing on obstetric danger signs to have better awareness and thereby reduce adverse maternal and neonatal outcomes.</p> Bijaya Ghimire, Pratima Pathak, Pratima Ghimire Copyright (c) 2022 Nepal Medical College Journal http://creativecommons.org/licenses/by/4.0 https://www.nepjol.info/index.php/nmcj/article/view/46029 Mon, 27 Jun 2022 00:00:00 +0000 Correlation between disc damage likelihood scale and vertical cup disc ratio with Automated Humphrey Perimetry in glaucoma patients attending a tertiary care hospital, Kathmandu, Nepal https://www.nepjol.info/index.php/nmcj/article/view/46036 <p>Glaucoma is the second leading ocular disease of irreversible blindness. Glaucoma is a progressive disorder and requires serial evaluation in order to monitor disease progression and optimize therapy. The objective of this study was to determine the correlation between disc damage likelihood scale (DDLS) and vertical cup disc ratio (VCDR) with the results of Humphrey field analyzer (HFA) parameters. This study was a descriptive, cross-sectional and observational study. A total of 104 eyes of 52 patients diagnosed with primary open angle glaucoma or normal tension glaucoma were examined. DDLS staging, VCDR and HFA 24-2 visual fields were obtained from the patients. The correlation of DDLS and VCDR with Mean deviation (MD), Pattern standard deviation (PSD) and Glaucoma hemi field test (GHT) of HFA was calculated by Pearson correlation coefficient (r). DDLS showed a coefficient correlation value of r = -.628, r = .391 and r = .395 (p = &lt;0.000) when correlated against HFA MD, PSD and GHT respectively. VCDR showed a coefficient correlation value of r = -.524, r = .317 and r = .221 when correlated against HFA MD, PSD and GHT respectively. DDLS has a better correlation compared to VCDR with all the parameters.</p> Pranisha Singh, Aditya Prasad Rijal Copyright (c) 2022 Nepal Medical College Journal http://creativecommons.org/licenses/by/4.0 https://www.nepjol.info/index.php/nmcj/article/view/46036 Mon, 27 Jun 2022 00:00:00 +0000 Determinants of hormonal contraceptive use and its effects among married women of reproductive age group in Kathmandu, Nepal https://www.nepjol.info/index.php/nmcj/article/view/46038 <p>The prevention of unwanted pregnancy, unsafe abortion and maternal mortality remains an important part of the practice of medicine. Several forms of hormonal contraception have been used to control female fertility. These are associated with benefits and risk. The current study aimed to study the determinants of hormonal contraceptive use and its effects among married women of reproductive age group in Kathmandu. This is a community based cross sectional study among 250 married women using hormonal contraceptives aged between 15-49 years residing in wards 8 and 9 of Gokarneshwor Municipality. The information was obtained using self-constructed structured questionnaire. Height, weight and blood pressure were recorded and hypertension was defined as per Joint National Committee (JNC) VII guidelines. Around one third of the participants were of 30-34 years and Depo-Provera was the most commonly used hormonal contraceptive. There were several side effects among the users and commonest were menstrual irregularities and weight gain. Around 47 participants had hypertension and 120 had raised BMI. The factors associated with hormonal contraceptive use were socioeconomic status, religion, BMI and monthly income of family of the study population. The present study provides valuable information regarding significant positive correlation of age, BMI and duration of hormonal contraceptive use with systolic and diastolic BP.</p> Supri Raj Shrestha, Vinutha Silvanus, Bharati Shakya Copyright (c) 2022 Nepal Medical College Journal http://creativecommons.org/licenses/by/4.0 https://www.nepjol.info/index.php/nmcj/article/view/46038 Mon, 27 Jun 2022 00:00:00 +0000 Morphometric profile of achilles tendon in male - a cadaveric study https://www.nepjol.info/index.php/nmcj/article/view/46039 <p>The Achilles tendon is a conjoined tendon of gastrocnemius and soleus muscles and occasionally may have a small contribution from plantaris muscle. Despite being the strongest and thickest tendon in the body it is a frequent site of degenerative changes, inflammation and rupture. The main objective of this study was to measure and analyze the various parameters of Achilles tendon in cadavers. An observational, descriptive study was conducted from August 2021 to February 2022 in the Department of Human Anatomy of Nepal Medical College Teaching Hospital, Attarkhel, Gokarneshwor – 8, Kathmandu, Nepal which included forty lower limbs of twenty male cadavers. The various parameters recorded were (a) mean length of right Achilles tendon was 16.65 ± 1.72 cm, (b) mean proximal width of right Achilles tendon was 5.50 ± 1.07 cm, (c) mean proximal circumference of right Achilles tendon was 10.67 ± 2.20 cm, (d) mean distal width of right Achilles tendon was 2.22 ± 0.54 cm, (e) mean distal circumference of right Achilles tendon was 4.27 ± 0.67 cm, (f ) mean length of left Achilles tendon was 16.35 ± 1.49 cm, (g) mean proximal width of left Achilles tendon was 5.25 ± 0.88 cm, (h) mean proximal circumference of left Achilles tendon was 10.57 ± 1.78 cm, (i) mean distal width of left Achilles tendon was 2.05 ± 0.27 cm and mean distal circumference of left Achilles tendon was 4.0 ± 0.42 cm. The present morphometric evaluation of Achilles tendon in cadavers can be of substantial help to clinicians before determining its pathological conditions and can also be of help to surgeons during the surgical repair and reconstruction of damaged tendon.</p> Chhiring Palmu Lama, Usha Chalise, Asim Shrestha, Shaligram Dhungel Copyright (c) 2022 Nepal Medical College Journal http://creativecommons.org/licenses/by/4.0 https://www.nepjol.info/index.php/nmcj/article/view/46039 Mon, 27 Jun 2022 00:00:00 +0000 Assessment of knowledge, attitude and practice of pharmacovigilance among people working in community pharmacy: a cross-sectional study at Banke District in Nepal https://www.nepjol.info/index.php/nmcj/article/view/46042 <p>The burden of ADRs is high globally and it accounts for considerable morbidity, mortality, and extra cost to the patients. Pharmacovigilance plays a significant role in the detection, assessment, understanding and reporting of ADRs. Objective of the study was to assess the knowledge, attitude and practice of pharmacovigilance among people working in community pharmacies in the Banke District. A prospective cross-sectional descriptive study was conducted among people working in community pharmacies in Banke district from February to March 2022 using a 20 item semi-structured questionnaire. Ethical approval was obtained from the institutional ethical review committee (501/078-079). Data were entered in Microsoft Office Excel 2010 and descriptive statistics like mean, frequency, percentage and standard deviation were calculated. Data were analyzed using SPSS-22 and data were presented as tables. Only 46 (22.89%) respondents knew the definition of pharmacovigilance. Mean knowledge score of the respondents was 2.87±2.05 out of the maximum possible score of 10. Only 40 (19.9%) respondents had knowledge score ≥50%. Out of 201, 180 (89.55%) respondents thought that reporting of adverse drug reaction will be beneficial in the future. A total of 136 (67.66%) respondents had positive attitude towards pharmacovigilance. One hundred and seventy seven (88.06%) had not seen ADR reporting form. A total of 166 (82.59%) respondents had poor practice towards pharmacovigilance. Majority of the respondents had poor knowledge, positive attitude and poor practice of pharmacovigilance. There is urgent need of educational programs on pharmacovigilance to raise awareness.</p> Aswani Chaudhary, Arvind Kumar Gupta, Balaram KC, Niraj Prasad Sah, Deependra Prasad Sarraf Copyright (c) 2022 Nepal Medical College Journal http://creativecommons.org/licenses/by/4.0 https://www.nepjol.info/index.php/nmcj/article/view/46042 Mon, 27 Jun 2022 00:00:00 +0000 Patterns of prescription and adverse drug reaction profile of Non- Steroidal Anti-Inflammatory Drugs at orthopedic out-patients department https://www.nepjol.info/index.php/nmcj/article/view/46045 <p>Non-steroidal Anti-inflammatory Drugs (NSAIDs) are the most prescribed drugs all over the world. These are used in the treatment of pain and inflammation. Systematic evaluation of prescription patterns and monitoring of adverse drug reactions is required to increase the therapeutic benefit and decrease the adverse effects of these drugs. An observational, cross-sectional study was conducted for 6 months from September 2021 to February 2022 in 300 patients prescribed least one NSAID to assess the prescription patterns and adverse drug reaction profile (ADR) of NSAIDs prescribed in the orthopedic outpatient department. Among enrolled patients 52% were female and 48% were male. The most common age group was 20-39. The average number of drugs per prescription was 2.89. A total of 868 drugs were prescribed, out of which 402 were NSAIDs (46.31%). Naproxen was the most prescribed agent (45.02%), followed by Diclofenac (17.17%). ADR was reported in 12% of patients. Most of the ADRs were due to Naproxen (72.18%) followed by Ibuprofen (16.66%). The gastrointestinal system was involved in maximum patients and the most common ADR was abdominal pain. Most of the drugs were prescribed by brand name 95.18%. Naproxen was the most prescribed NSAID and responsible for most ADRs. There was a higher prevalence of irrational prescribing, polypharmacy, and underreporting of ADR. A strategy must be developed and implemented for prescribing and rational use of NSAIDs and monitoring their harmful effects.</p> Ganesh Prasad Neupane, Maya Rai, Poojan Kumar Rokaya Copyright (c) 2022 Nepal Medical College Journal http://creativecommons.org/licenses/by/4.0 https://www.nepjol.info/index.php/nmcj/article/view/46045 Mon, 27 Jun 2022 00:00:00 +0000 Role of colour Doppler ultrasonography in the evaluation of deep vein thrombosis of peripheral limbs at a tertiary care centre in Kathmandu https://www.nepjol.info/index.php/nmcj/article/view/46046 <p>Deep venous thrombosis is the development of blood clots in the deep veins. The management of deep venous thrombosis has been irreversibly altered after the introduction of Doppler ultrasound. This study aims to find out the prevalence of deep vein thrombosis of lower limbs diagnosed with colour Doppler ultrasonography at a tertiary care centre. A descriptive cross-sectional study was conducted in the Department of Radiology at a tertiary care hospital from October, 2021 to March, 2022. The study was conducted among 100 patients with clinically suspected deep venous thrombosis. Data were entered and analyzed using Microsoft Excel. Point estimate at 95.0% confidence limits was calculated and results were expressed in frequency and proportion for binary data. Among 100 patients, deep venous thrombosis was diagnosed in 88 (88.0%) patients (95% CL: 81.63-94.37). The patients had a mean age of 48.4±1.6 years. Out of 88 patients, 46 (52.3%) were male and 42 (47.7%) were female. Seventy-three (82.9%) patients had acute DVT. Multiple contiguous veins were predominantly involved (75.0%) than isolated veins (25.0%). Coexisting pathological conditions were seen in 41 cases (46.6%). The prevalence of deep vein thrombosis of lower limbs diagnosed with colour Doppler ultrasonography was higher when compared to other similar reported literatures.</p> Abhushan Siddhi Tuladhar, Pingala Khadka, Sammi Joshi, Keshika Koirala, Sunil Pradhan, Amit Shrestha Copyright (c) 2022 Nepal Medical College Journal http://creativecommons.org/licenses/by/4.0 https://www.nepjol.info/index.php/nmcj/article/view/46046 Mon, 27 Jun 2022 00:00:00 +0000