Comparative Study of Clinical Profile and Outcome Among Variceal and Nonvariceal Bleeding in a Tertiary Referral Hospital of Nepal During Covid Pandemic

Authors

  • Binod Karki Nepalese Army Institute of Health Sciences, Shree Birendra Hospital, Kathmandu Nepal https://orcid.org/0000-0002-4650-9561
  • Tshering Wagdi Sherpa Nepalese Army Institute of Health Sciences, Shree Birendra Hospital, Kathmandu Nepal
  • Rajeeb Kumar Deo Nepalese Army Institute of Health Sciences, Shree Birendra Hospital, Kathmandu Nepal
  • Egesh Aryal Nepalese Army Institute of Health Sciences, Shree Birendra Hospital, Kathmandu Nepal
  • Binit Upadhyaya Regmi Nepalese Army Institute of Health Sciences, Shree Birendra Hospital, Kathmandu Nepal
  • Alisha Adhikari Nepalese Army Institute of Health Sciences, Shree Birendra Hospital, Kathmandu Nepal
  • Srijana Katawal Nepalese Army Institute of Health Sciences, Shree Birendra Hospital, Kathmandu Nepal
  • Sujit Kumar Mandal Nepalese Army Institute of Health Sciences, Shree Birendra Hospital, Kathmandu Nepal

DOI:

https://doi.org/10.3126/nmj.v5i1.44527

Keywords:

Non variceal, Upper GI bleeding, Variceal

Abstract

Introduction: Upper Gastrointestinal Bleeding is a common medical emergency that is broadly classified into variceal and non-variceal bleeding. Preendoscopicemperical treatment is based on clinical findings and laboratory parameters. The article aimed to compare these parameters among variceal and non-variceal bleeding.

Materials and Methods: This is a retrospective descriptive study conducted in a tertiary level referral hospital after taking approval from the Institutional review board. The data included was from September 2020 to August 2021. All patients with relevant data who underwent upper GI endoscopy were enrolled. The clinical and laboratory parameters were compared using appropriate statistical tests.

Results: A total of 85 patients were studied with 40 (47.06%) in the variceal and 45 (52/94%) in the non-variceal group. Significantly more patients in the variceal bleeding group had a history of alcohol consumption (85% vs 60%) and smoking history (52.50 % vs 31.10%) compared to the non-variceal group. Jaundice, ascites, splenomegaly, low platelet count, and high INR all were predictors of variceal bleeding (p<0.005). In the variceal group, 39 (97.5%) needed endo therapy compared to only 4 (8.9%) in the non-variceal group.

Conclusions: Clinical and laboratory parameters differ significantly in the variceal and non-variceal groups which can guide the pre-endoscopic management of the patients.

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Author Biographies

Binod Karki, Nepalese Army Institute of Health Sciences, Shree Birendra Hospital, Kathmandu Nepal

Associate Professor, Department of Medicine

Tshering Wagdi Sherpa, Nepalese Army Institute of Health Sciences, Shree Birendra Hospital, Kathmandu Nepal

Department of Medicine

Rajeeb Kumar Deo, Nepalese Army Institute of Health Sciences, Shree Birendra Hospital, Kathmandu Nepal

Department of Medicine

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Published

2022-06-30

How to Cite

Karki, B., Sherpa, T. W., Deo, R. K., Aryal, E., Regmi, B. U., Adhikari, A., Katawal, S., & Mandal, S. K. (2022). Comparative Study of Clinical Profile and Outcome Among Variceal and Nonvariceal Bleeding in a Tertiary Referral Hospital of Nepal During Covid Pandemic. Nepalese Medical Journal, 5(1), 506–509. https://doi.org/10.3126/nmj.v5i1.44527

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Section

Original Articles