TY - JOUR AU - Khaniya, Bishal PY - 2021/06/30 Y2 - 2024/03/28 TI - Histopathological Pattern of Gynecological Malignancies at Tribhuvan University Teaching Hospital, Nepal: A 3 years Study JF - Nepalese Medical Journal JA - Nep. Med. J. VL - 4 IS - 1 SE - Original Articles DO - 10.3126/nmj.v4i1.37717 UR - https://www.nepjol.info/index.php/nmj/article/view/37717 SP - 442-445 AB - <p><strong>Introduction</strong>: Gynecological malignancies include malignancies affecting the female reproductive organs ovary, cervix, body of uterus, vulva, vagina, and gestational trophoblastic neoplasia.</p><p><strong>Materials and Methods: </strong>This is a hospital-based retrospective observational study of histopathological confirmed gynecological malignancies conducted in the department of Obstetrics and Gynecology, TUTH, Maharajgunj, Kathmandu for 3 years from April 2016 to March 2018.</p><p><strong>Results:</strong> Among 314 cases enrolled in the study, the most common gynecological malignancy was of ovary (50.63%), followed by the cervix (30.25%), endometrium (9.23%), (4.77%) gestational trophoblastic neoplasia (3.82%), and fallopian tube (1.27%). 71% of the gynecological malignancies presented in early-stage and 29% in late-stage. The most common histopathological diagnosis of ovarian cancer was serous cystadenocarcinoma (30.18%), cervical cancer was squamous cell non-keratinizing type (46.3%), endometrial carcinoma was endometrioid adenocarcinoma (55%), vulval carcinoma was squamous cell carcinoma (86%), fallopian tube carcinoma (100%). The mean age of gynecological malignancy was 49.06 +- 10.08 years.</p><p><strong>Conclusions: </strong>Screening of gynecological malignancy is necessary to identify the disease in early-stage to decrease maternal morbidity and mortality.</p> ER -