Immunohistochemistry of Lymphocytes Subsets in Subclinical Experimental Paratuberculosis in Goats
The present experiment was carried out to find out the lymphocytes subsets reactions in experimentally induced subclinical paratuberculosis in goats. Twelve goats of 8-12 weeks age were infected with 4.23 x 109 Mycobacterium avium paratuberculosis on 8 occasions. Seven goats were kept as in-contact controls and 4 as uninfected controls. Immunohitochemistry for detection of cellular reaction of CD2+, CD4+, CD8+, CD25+, MHC I and MHCII in the lymphocytes present in the intestine and lymph node revealed more reactive cells in the infected goats as compared with the in-contact and infected control goats.
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