Immunohistochemistry of Lymphocytes Subsets in Subclinical Experimental Paratuberculosis in Goats

  • U. M. Singh Division of Pathology, IVRI
  • B. N. Tripathi Division of Pathology, IVRI
  • O. P. Paliwal Division of Pathology, IVRI
Keywords: Paratuberculosis, Immunohistochemistry, Lymphocyte subsets MHC I, MHCII

Abstract

 The present experiment was carried out to find out the lymphocytes subsets reactions in experimentally induced subclinical paratuberculosis in goats. Twelve goats of 8-12 weeks age were infected with 4.23 x 109 Mycobacterium avium paratuberculosis on 8 occasions. Seven goats were kept as in-contact controls and 4 as uninfected controls. Immunohitochemistry for detection of cellular reaction of CD2+, CD4+, CD8+, CD25+, MHC I and MHCII in the lymphocytes present in the intestine and lymph node revealed more reactive cells in the infected goats as compared with the in-contact and infected control goats.

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Abstract
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Published
2019-12-01
How to Cite
Singh, U., Tripathi, B., & Paliwal, O. (2019). Immunohistochemistry of Lymphocytes Subsets in Subclinical Experimental Paratuberculosis in Goats. Nepalese Veterinary Journal, 36, 1-7. https://doi.org/10.3126/nvj.v36i0.27745
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Articles