Level of Serum Electrolytes in Chronic Alcoholic Patients

  • Mithileshwer Raut Maharajgunj Medical Campus, IOM, TUTH
  • Sangita Ghimire Tribhuvan University Teaching Hospital (TUTH), Kathmandu
  • Prashant Regmi Nepal Medical College, Jorpati
  • Sanjay Kumar Raut Tri-Chandra College, Kathmandu
  • Bharat Jha Maharajgunj Medical Campus, IOM, TUTH
Keywords: Alcoholism, hyponatremia, hypokalemia

Abstract

BACKGROUND: The aim of this study is to establish serum levels of sodium, potassium, magnesium, calcium and phosphorus in chronic alcoholic patients.

METHODS: This cross-sectional study was conducted in Tribhuvan University Teaching Hospital (TUTH).  A total of 90 chronic alcoholic patients visiting to psychiatry department of TUTH were included in the study. Age of patients ranges from 20-50 years. Study also included 90 non-alcoholic healthy controls that were age matched.

RESULTS: Among the 90 chronic alcoholic patients and 90 normal healthy controls, majority of patients (95.5%) and controls (82%) were male, only few patients were female (4.5%). The mean age of the cases and controls were 35.42 ± 5.6 years, 34.53 ± 3.5 years respectively. In this study, the mean values of Serum Sodium and Potassium were lower in cases (133.58 ± 7.8, sodium and 3.64 ± 0.65, potassium) as compared to controls ( 139.43 ± 3.85, sodium and 4.15 ± 0.43, potassium) with the significant correlation in both groups (p<0.001). Calcium, phosphorus and magnesium level was depleted in cases compared to control groups.

CONCLUSIONS: Hyponatremia and hypokalemia are the most common electrolyte abnormalities observed in chronic alcoholic patients.

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Author Biographies

Mithileshwer Raut, Maharajgunj Medical Campus, IOM, TUTH
Department of Biochemistry, Lecturer
Sangita Ghimire, Tribhuvan University Teaching Hospital (TUTH), Kathmandu
Department of Microbiology, Medical Laboratory Technologist
Prashant Regmi, Nepal Medical College, Jorpati
Department of Biochemistry, Assistant Professor
Sanjay Kumar Raut, Tri-Chandra College, Kathmandu
Department of Chemistry, Assistant Professor
Bharat Jha, Maharajgunj Medical Campus, IOM, TUTH
Department of Biochemistry, Professor
Published
2015-10-02
How to Cite
Raut, M., Ghimire, S., Regmi, P., Raut, S., & Jha, B. (2015). Level of Serum Electrolytes in Chronic Alcoholic Patients. Annals of Clinical Chemistry and Laboratory Medicine, 1(2), 31-34. https://doi.org/10.3126/acclm.v1i2.13330
Section
Original Articles