Correlation of Serum zinc with TSH in hyperthyroidism

Authors

  • Satwika Sinha Assistant Professor, Department Of Biochemistry Calcutta National Medical College
  • Kaushik Kar Assistant Professor, Department Of Biochemistry Calcutta National Medical College
  • Anindya Dasgupta Professor, Department Of Biochemistry Calcutta National Medical College
  • Saubhik Basu Post Graduate Student, Department Of Biochemistry Calcutta National Medical College
  • Sukanta Sen Post Doctoral Student, Department of Clinical & Experimental Pharmacology Catcutta School of Tropical Medicine

DOI:

https://doi.org/10.3126/ajms.v7i1.12895

Keywords:

metabolic disease

Abstract

Aims and Objectives: Trace elements may have a role in progression of hyperthyroidism. We planned to estimate the serum zinc, copper and ceruloplasmin in hyperthyroids.

Materials and Methods: 41 hyperthyroid patients and 32 control subjects were taken for the study. Serum T4,TSH ,zinc, copper and ceruloplasmin were estimated in them. T4 and TSH were estimated by ELISA method. Zinc and copper were estimated by colorimetric method. Serum ceruloplasmin were estimated by  Ravins method.

Results: Significant decrease of TSH (p<0.0001)and zinc(p<0.0001) were found in hyperthyroids in comparision to controls. Serum copper and ceruloplasmin were significantly  elevated(p<0.0001) in them. Significant positive correlation  between TSH and zinc was observed in case group.

Conclusion: Zinc defficiency may contribute to the worsening of hyperthyroidism. Zinc supplementation may improve the condition.

Asian Journal of Medical Sciences Vol.7(1) 2015 66-69

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Published

2015-08-28

How to Cite

Sinha, S., Kar, K., Dasgupta, A., Basu, S., & Sen, S. (2015). Correlation of Serum zinc with TSH in hyperthyroidism. Asian Journal of Medical Sciences, 7(1), 66–69. https://doi.org/10.3126/ajms.v7i1.12895

Issue

Vol. 7 No. 1 (2016)

Section

Original Articles

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