Rapid diagnosis of neonatal sepsis in Pediatric population in tertiary care hospital, Durg

Authors

  • Shiv Kumar Chandrakar Associate Professor, Department of Pathology, CCM Medical College & Hospital, Durg http://orcid.org/0000-0001-6213-3288
  • Smita Bawankar Assistant Professor, Department of Microbiology, CCM Medical College & Hospital, Durg http://orcid.org/0000-0003-3755-1378
  • Animesh Panda Assistant Professor, Department of Microbiology, CCM Medical College & Hospital, Durg
  • Dhruba Hari Chandi Demonstrator, Department of Microbiology, CCM Medical College & Hospital, Durg

DOI:

https://doi.org/10.3126/ajms.v7i3.14073

Keywords:

Bacteraemia, Blood cultures, Rapid diagnostic test & CCMMCH, Durg.

Abstract

Background: In under developing country Septicemia in infants to be of common occurrence with high morbidity & mortality.

Aims and Objectives:  Detection of rapid method for diagnosis of sepsis in paediatric age groups.

Materials and Methods : Clinically suspected 369 cases of Bacteraemia in neonates, infants & children admitted as inpatients at CCM Medical College & Hospital, Durg & 45 healthy children as control were included in the present study. The cases were investigated by blood culture & 5 rapid tests Viz total leucocyte count (TLC), immature to total neutrophil ( I:T) ratio, C – reactive protein (CRP), ESR & Grams smears of Buffy coat for organisms.

Results :  Blood cultures were positive in 171 (46.34%) of 369 cases and negative organisms was 55.55% as against 44.44% of Gram positive bacteria. The most common isolates were Staph epidermides (24.56%) and Staph aureus (16.37%) with overall staphylococcal prevalence of 40.93% followed by gram negative bacteria, S.typhi (14.61%) E.coli 11.11% & Ps.auroginosa 10.52%.

Conclusion : The rapid tests were evaluated in blood culture positive & negative cases CRP yielded maximum sensitivity of 70.76%, Specificity of 76.26% & positive predictive accuracy of 72.02%. Combination of 2 tests did not reveal any significant advantage over single CRP test.

Asian Journal of Medical Sciences Vol. 7(3) 2016 94-96

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Published

2016-01-06

How to Cite

Chandrakar, S. K., Bawankar, S., Panda, A., & Chandi, D. H. (2016). Rapid diagnosis of neonatal sepsis in Pediatric population in tertiary care hospital, Durg. Asian Journal of Medical Sciences, 7(3), 94–96. https://doi.org/10.3126/ajms.v7i3.14073

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Section

Original Articles