Role of tranexamic acid to reduce blood loss and transfusion of allogeneic blood in the field of surgery

Authors

  • Indra K. Shrestha Resident, Department of Anesthesiology, Second Affiliated Hospital of Kunming Medical University, Yunnan, Kunming, Dianmian Avenue 374, 650101, China https://orcid.org/0000-0003-2379-2496
  • Yong Yu Si Professor and Director, Department of Anesthesiology, Second Affiliated Hospital of Kunming Medical University, Yunnan, Kunming, Dianmian Avenue 374, 650101, China https://orcid.org/0000-0002-3058-4284
  • Jian Ping Tao Professor and Vice Director, Department of Anesthesiology, Second Affiliated Hospital of Kunming Medical University, Yunnan, Kunming, Dianmian Avenue 374, 650101, China https://orcid.org/0000-0001-5511-6834

DOI:

https://doi.org/10.3126/ajms.v11i2.26205

Keywords:

Tranexamic acid, Blood loss, Transfusion, Surgery

Abstract

Tranexamic acid is widely used as an antifibrinolytic drug to reduce blood loss intraoperative and postoperative time periods as well as to reduce transfusion of allogeneic blood. After releasing in the market, multidisciplinary surgeries have wide use of tranexamic acid due to its antifibrinolytic effect to reduce bleeding and transfusion of blood. In literature, there were mentioned a few adverse effects like thromboembolism, seizure, anaphylactic reaction, etc which are still unsolved questions to date. The aim of this review to minimize the blood loss from acute bleeding in different situations by updating the doses used in a different clinical scenario,since the release of tranexamic acid. It also gives an idea about appropriate doses to reduce blood loss, need for blood transfusion, minimize adverse effects and to understand the wide scope of application of TXA to date.

Downloads

Download data is not yet available.
Abstract
543
PDF
674
Cover 11(2)

Downloads

Published

2020-02-29

How to Cite

Shrestha, I. K., Si, Y. Y., & Tao, J. P. (2020). Role of tranexamic acid to reduce blood loss and transfusion of allogeneic blood in the field of surgery. Asian Journal of Medical Sciences, 11(2), 89–95. https://doi.org/10.3126/ajms.v11i2.26205

Issue

Vol. 11 No. 2 (2020)

Section

Review Articles

License

Authors who publish with this journal agree to the following terms:

  1. The journal holds copyright and publishes the work under a Creative Commons CC-BY-NC license that permits use, distribution and reprduction in any medium, provided the original work is properly cited and is not used for commercial purposes. The journal should be recognised as the original publisher of this work.
  2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
  3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).