Endogenous Hypercortisolism in recurrent Central Serous Chorioretinopathy

Authors

DOI:

https://doi.org/10.3126/ajms.v12i2.31753

Keywords:

Central Serous Chorioretinopathy, CSCR, Cortisol, Hypercortisolism

Abstract

Background: Central Serous Chorioretinopathy (CSCR) is an important cause of nonsurgical retinopathy leading to moderate to severe visual loss. Almost 50% cases undergo recurrence, and one of the recognizable risk factors is endogenous hypercortisolism.

Aims and Objective: Our study intended to its presence in recurrent CSCR patients compared to non-chorioretinal disorder.

Materials and Methods: Eighteen-month cross-sectional comparative study done on recurrent CSCR patients and matched refractive error patients comprised the comparison group. Use of exogenous steroids and diagnosed conditions of hypercortisolism were excluded. Sample size for both the groups was 34 in each. After taking history and performing ocular examination, blood samples for serum cortisol estimation collected in the morning and in the evening in patients of both the groups. Results analyzed using standard statistical methods.

Results: All patients of recurrent CSCR were males. The mean serum levels of cortisol were higher than laboratory reference range during both times of the day in recurrent CSCR patients, and these levels were significantly higher than those in the comparison groups.

Conclusion: Recurrent CSCR patients have higher level of endogenous cortisol compared to the non-chorioretinal patients, and its early recognition and management would certainly benefit the patients.

Downloads

Download data is not yet available.
Abstract
213
PDF
269
Cover AJMS 12(2)

Downloads

Published

2021-02-01

How to Cite

Mukherji, S., Karmakar, S., & Dasgupta, S. (2021). Endogenous Hypercortisolism in recurrent Central Serous Chorioretinopathy. Asian Journal of Medical Sciences, 12(2), 49–53. https://doi.org/10.3126/ajms.v12i2.31753

Issue

Vol. 12 No. 2 (2021)

Section

Original Articles

License

Authors who publish with this journal agree to the following terms:

  1. The journal holds copyright and publishes the work under a Creative Commons CC-BY-NC license that permits use, distribution and reprduction in any medium, provided the original work is properly cited and is not used for commercial purposes. The journal should be recognised as the original publisher of this work.
  2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
  3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).