Comparison of capillary blood glucose level at 1 h after induction of general anesthesia in children receiving intraoperatively either Ringer’s lactate with glucose 1% or Ringer’s lactate alone
DOI:
https://doi.org/10.3126/ajms.v13i7.42569Keywords:
Hyperglycemia, Hypoglycemia, Intravenous fluid, Pediatric, PerioperativeAbstract
Background: Perioperative fluid therapy in children is quite challenging job for anesthesiologists. Variable glycemic control has been reported in the literature regarding the use of balanced electrolyte solution with or without 1–2% glucose supplementation.
Aims and Objectives: Hence, this study was planned to determine the capillary blood glucose level (CBG) in the intraoperative period at 1 h after induction of general anesthesia in children (1–6 years of age) receiving either Ringer’s lactate (RL) with glucose 1% or RL alone.
Materials and Methods: A total of 60 patients of either gender, aged 1–6 years, of American Society of Anesthesiologists Physical Status Classes 1 and 2 were included for this interventional study. All children received protocolized general anesthesia with strict adherence to standard fasting guidelines. The children received either RL alone (Group A, n=30) or RL plus 1% glucose solution (Group B, n=30) as intraoperative fluid. The pre-operative CBG was recorded. Intraoperative fluid was given at 10 mL/kg/hr. The CBG was checked again at 30 min and 1 h after induction of anesthesia. The glycemic status at 1 h in the intraoperative period was compared (primary outcome) between the two groups.
Results: The hemodynamics and intraoperative consumption of fluid were comparable between the groups. The mean CBG values at 30 min and at 1st h were considerably higher in groups receiving RL with 1% glucose compared with those receiving RL alone. However, these differences were not clinically significant. No adverse event was observed.
Conclusion: RL alone or RL plus glucose 1% can be used as intraoperative fluid in children (1–6 years of age). None developed clinically significant hypoglycemia or hyperglycemia. However, the optimal amount of glucose which can be safely used in the perioperative period needs to be determined with a larger trial.
Downloads
95
160
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2022 Asian Journal of Medical Sciences
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Authors who publish with this journal agree to the following terms:
- The journal holds copyright and publishes the work under a Creative Commons CC-BY-NC license that permits use, distribution and reprduction in any medium, provided the original work is properly cited and is not used for commercial purposes. The journal should be recognised as the original publisher of this work.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
