A prospective audit to assess the feasibility of sentinel lymph node biopsy and/or low axillary sampling in clinicoradiologically node-negative axilla for early breast carcinoma

Authors

  • Abasaheb Madhukar Tidake Senior Resident, Department of General Surgery, Government Medical College and Hospital, Aurangabad, Maharashtra, India https://orcid.org/0000-0002-4566-7090
  • Anagha S Varudkar Professor and Head, Department of Surgical Oncology, Government Medical College and Cancer Hospital, Aurangabad, Maharashtra, India
  • Balaji Shankarrao Mane Assistant Professor, Department of Otorhinolaryngology, Ashwini Rural Medical College and Research Centre, Solapur, Maharashtra, India https://orcid.org/0000-0002-4566-7090

DOI:

https://doi.org/10.3126/ajms.v14i12.57240

Keywords:

Sentinel; Lymph node biopsy; Axilla; Breast carcinoma

Abstract

Background: Sentinel lymph node (SLN) dissection was designed to minimize side effects of lymph node surgery but still offer outcomes of axillary lymph node dissection.

Aims and Objectives: Our study is designed to determine whether SLN resection achieves the same therapeutics outcome as complete axillary dissection but with fewer side effects for node-negative axilla in clinicoradiologically operable breast cancer patients.

Materials and Methods: Duration-based prospective observational study was carried out at the General Surgery and Surgical Oncology Department at Government Medical College and Hospital, Aurangabad with a duration of 2 ½ years from July 2019 to January 2022. A total of 36 patients of breast cancers with stages T1-T2, N0 with clinically and radiologically negative axilla from July 2019 to January 2022 duration were included in our study.

Results: When the histopathological status of axillary lymph nodes was compared to the histopathology of SLNs it was seen that out of 36 patients, the histopathology of sentinel node was positive in 10 patients (10/36) however the rest of the axilla was positive in 6 cases and negative in 4 cases and the histopathology sentinel node was negative in 26 patients out of 36 cases (26/36) however the rest of the axilla was also negative in 24 cases and positive in 2 cases.

Conclusion: SLN biopsy using methylene blue dye alone is a highly reliable and predictable technique to stage the axilla in breast cancer patients as this study shown a low false-negative rate (7.69%). This technique may help to avoid complete axillary lymph node dissection in sentinel node-negative patients thereby minimizing the morbidity of axillary lymph node dissection. This study demonstrates that sentinel node localization is possible with methylene blue dye alone.

Downloads

Download data is not yet available.
Abstract
105
PDF
122

Downloads

Published

2023-12-01

How to Cite

Abasaheb Madhukar Tidake, Anagha S Varudkar, & Balaji Shankarrao Mane. (2023). A prospective audit to assess the feasibility of sentinel lymph node biopsy and/or low axillary sampling in clinicoradiologically node-negative axilla for early breast carcinoma. Asian Journal of Medical Sciences, 14(12), 192–197. https://doi.org/10.3126/ajms.v14i12.57240

Issue

Section

Original Articles