Risk factor profile and extubation outcomes in critically ill patients. A single-center prospective observational study

Authors

  • Abdul Waheed Mir Additional Professor, Department of Critical Care, Sher I Kashmir Institute of Medical Sciences, Srinagar, Jammu and Kashmir, India https://orcid.org/0000-0003-4467-507X
  • Shafat A Mir Associate Professor, Department of Anesthesiology, Sher I Kashmir Institute of Medical Sciences, Srinagar, Jammu and Kashmir, India https://orcid.org/0000-0001-9014-6043
  • Falak Ara Senior Resident, Department of Anesthesiology, Sher I Kashmir Institute of Medical Sciences, Srinagar, Jammu and Kashmir, India https://orcid.org/0009-0007-7124-006X
  • Rashid Fazli Senior Resident, Department of Anesthesiology, Sher I Kashmir Institute of Medical Sciences, Srinagar, Jammu and Kashmir, India https://orcid.org/0009-0009-4297-6451
  • Sahu Mushtaq Senior Resident, Department of Anesthesiology, Sher I Kashmir Institute of Medical Sciences, Srinagar, Jammu and Kashmir, India https://orcid.org/0009-0001-3053-915X
  • M Akbar Shah Additional Professor, Department of Critical Care, Sher I Kashmir Institute of Medical Sciences, Srinagar, Jammu and Kashmir, India https://orcid.org/0000-0003-0172-8282
  • Khalid Sofi Additional Professor, Department of Anesthesiology, Sher I Kashmir Institute of Medical Sciences, Srinagar, Jammu and Kashmir, India

DOI:

https://doi.org/10.3126/ajms.v15i3.60683

Keywords:

Extubation; ICU; Mechanical ventilation

Abstract

Background: The problem of extubation failure (EF) remains unexplored in low-resource settings, where predicting the extubation outcomes are more challenging.

Aims and Objectives: This study investigates the incidence of EF and its predictors among patients who received mechanical ventilation (MV) in a tertiary care intensive care unit (ICU).

Materials and Methods: This is a prospective observational study of 130 patients ≥18 years of age receiving MV for ≥48 h and tolerating spontaneous breathing trials in the ICU of a low-resource setting. We collected data on the baseline characteristics and clinical profiles. Patients were categorized into EF and extubation success (ES) groups. Multivariate logistic regression analyses were performed to identify independent predictors for EF. A p value of <0.05 is considered statistically significant.

Results: We included 130 patients, and 43 (35.3%) had developed EF. The identified predictors for EF: Moderate to copious secretions (adjusted odds ratio [AOR]: 3.426 [95% confidence interval [CI] 1.281–10.82]), age >60 years of age ([AOR]: 4.135 [95% CI 1.294–11.93]), and prolonged duration of MV ≥10 days ([AOR]: 4.571 [95% CI 1.392–15.33]).

Conclusion: Moderate to copious secretions, patients >60 years of age, and prolonged duration of MV ≥10 days were the best predictors of EF.

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Published

2024-03-01

How to Cite

Abdul Waheed Mir, Shafat A Mir, Falak Ara, Rashid Fazli, Sahu Mushtaq, M Akbar Shah, & Khalid Sofi. (2024). Risk factor profile and extubation outcomes in critically ill patients. A single-center prospective observational study. Asian Journal of Medical Sciences, 15(3), 75–79. https://doi.org/10.3126/ajms.v15i3.60683

Issue

Vol. 15 No. 3 (2024)

Section

Original Articles

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Copyright (c) 2024 Asian Journal of Medical Sciences

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