Chemical profiling and antioxidant activities of essential oil from rhizomes of Acorus calamus L.

  • Sumnath Khanal Central Department of Chemistry, TU
  • Devi Prasad Bhandari Natural Products Research Laboratory, Thapathali, Kathmandu
  • Laxman Bhandari Natural Products Research Laboratory, Thapathali, Kathmandu
  • Achyut Adhikari Central Department of Chemistry, Tribhuvan University, Kathmandu
Keywords: Acorus calamus L., DPPH assay, Essential oil, GC-MS, IC50

Abstract

Background and Aims: Acorus calamus L. is an indigenous herb in Nepal. It belongs to family Acoraceae and grows in wet land with scented rhizomes. It is also known as Sweet flag in English and commonly as Bojho in Nepal. The present investigation reveals the chemical compositions and antioxidant activity of rhizome essential oil of A. calamus. Methods: Essential oil of rhizomes of Acorus calamus L. from Kaski district, Nepal was extracted by hydrodistillation method and volatile constituents were analyzed Gas chromatography-Mass spectrometry. The antioxidant potential of essential oil was analyzed by 1,1-Diphenyl-2-Picrylhydrazyl (DPPH) scavenging assay. Results: A GC-MS analysis revealed the presence of β-asarone (22.38%), α-asarone (14.97%), 1-(4,6-dimethoxy-2,3-dimethylphenyl ethanone (14.24%), Isoelemicin (5.68%), cis-Methylisoeugenol (4.26%), α-calacorene (4.16%), and other 20 minor components. From DPPH assay, half maximal inhibitory concentration (IC50) value of essential oil was found to be 108.71 µg/mL. Conclusions: These findings have strengthened the A. calamus L. is good source of compounds like β-asarone, α-asarone and can be used as potential antioxidants.

BIBECHANA 17 (2020) 89-95

Downloads

Download data is not yet available.
Abstract
373
pdf
276
Published
2020-01-01
How to Cite
Khanal, S., Bhandari, D., Bhandari, L., & Adhikari, A. (2020). Chemical profiling and antioxidant activities of essential oil from rhizomes of Acorus calamus L. BIBECHANA, 17, 89-95. https://doi.org/10.3126/bibechana.v17i0.25201
Section
Research Article