Thermal properties of normal and sickled hemoglobin protein

Keywords: Thermodynamic properties, Sickle cell, Molecular dynamics, Hemoglobin protein, PDB

Abstract

Thermodynamic properties of sickled and normal hemoglobin protein are considered within the framework of classical molecular dynamics. Here we have studied the specific heat capacity and RMSD (Root Mean Square Deviation) of both types of hemoglobin protein. Our investigation reveals that the specific heat capacity and RMSD for oxygenated hemoglobin protein is higher than those of de-oxygenated sickle hemoglobin protein. It is also observed that the specific heat capacity and RMSD values of sickle hemoglobin protein decrease with a rise in temperature.

BIBECHANA 18 (1) (2021) 140-148

Downloads

Download data is not yet available.
Abstract
241
pdf
60
Published
2021-01-01
How to Cite
Powrel, J., & Adhikari, N. (2021). Thermal properties of normal and sickled hemoglobin protein. BIBECHANA, 18(1), 140-148. https://doi.org/10.3126/bibechana.v18i1.29750
Section
Research Article